6N1C
Crystal structure of Inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006796 | biological_process | phosphate-containing compound metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006796 | biological_process | phosphate-containing compound metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006796 | biological_process | phosphate-containing compound metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006796 | biological_process | phosphate-containing compound metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 201 |
| Chain | Residue |
| A | LYS143 |
| A | ASP144 |
| A | GLU146 |
| A | LYS149 |
| A | HOH303 |
| A | HOH373 |
| A | HOH393 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| F | HOH338 |
| A | GLU146 |
| A | HOH305 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue MPD A 203 |
| Chain | Residue |
| A | PHE51 |
| A | PRO53 |
| A | HIS130 |
| A | SER134 |
| A | HOH317 |
| A | HOH351 |
| A | HOH362 |
| B | PRO28 |
| B | MET46 |
| B | THR47 |
| B | THR48 |
| B | ALA49 |
| D | MET117 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ALA A 204 |
| Chain | Residue |
| A | PRO79 |
| B | HOH316 |
| D | VAL78 |
| E | HOH464 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MRD B 201 |
| Chain | Residue |
| A | HIS25 |
| A | GLY26 |
| A | PHE51 |
| B | HIS25 |
| B | GLY26 |
| B | HOH312 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue MPD B 202 |
| Chain | Residue |
| A | PRO28 |
| A | THR48 |
| A | HOH337 |
| B | PRO53 |
| B | HIS130 |
| B | SER134 |
| B | HOH339 |
| F | VAL78 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue MPD C 201 |
| Chain | Residue |
| C | PRO53 |
| C | HIS130 |
| C | SER134 |
| C | HOH325 |
| E | VAL78 |
| F | PRO28 |
| F | THR48 |
| F | HOH336 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 201 |
| Chain | Residue |
| D | ASP71 |
| D | ASP103 |
| D | ALA104 |
| D | LYS105 |
| D | HOH334 |
| D | HOH377 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue MPD D 202 |
| Chain | Residue |
| A | MET117 |
| D | PHE51 |
| D | PRO53 |
| D | SER134 |
| D | HOH304 |
| D | HOH346 |
| E | THR47 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue ALA E 301 |
| Chain | Residue |
| C | HOH312 |
| E | VAL78 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MPD E 302 |
| Chain | Residue |
| D | HIS25 |
| D | GLY26 |
| D | PHE51 |
| E | HIS25 |
| E | GLY26 |
| E | HOH439 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue MPD E 303 |
| Chain | Residue |
| C | PRO77 |
| C | VAL78 |
| C | MET117 |
| D | PRO28 |
| D | THR47 |
| D | THR48 |
| D | ALA49 |
| E | PHE51 |
| E | PRO53 |
| E | SER134 |
| E | HOH409 |
| E | HOH471 |
| E | HOH475 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue MPD F 201 |
| Chain | Residue |
| B | PRO77 |
| B | MET117 |
| C | THR47 |
| F | HIS130 |
| F | SER134 |
| F | HOH339 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue NA F 202 |
| Chain | Residue |
| A | GLN129 |
| F | LYS143 |
| F | GLU146 |
| F | LYS149 |
| F | HOH322 |
| F | HOH353 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DGDPVDV |
| Chain | Residue | Details |
| A | ASP66-VAL72 |
