Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | binding site for residue TZ0 A 801 |
Chain | Residue |
A | LEU484 |
A | ASN568 |
A | ARG627 |
A | LEU630 |
A | ALA640 |
A | ASP641 |
A | PHE642 |
A | HOH910 |
A | ALA512 |
A | LYS514 |
A | GLU531 |
A | MET535 |
A | ILE545 |
A | GLU562 |
A | TYR563 |
A | ALA564 |
site_id | AC2 |
Number of Residues | 11 |
Details | binding site for residue TZ0 B 801 |
Chain | Residue |
B | LEU484 |
B | ALA512 |
B | LYS514 |
B | GLU531 |
B | GLU562 |
B | TYR563 |
B | ALA564 |
B | LEU630 |
B | ALA640 |
B | ASP641 |
B | PHE642 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
Chain | Residue | Details |
A | LEU484-LYS514 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 40 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
A | ASP468-ALA488 | |
B | ASP468-ALA488 | |
Chain | Residue | Details |
A | LYS714 | |
B | LYS714 | |
site_id | SWS_FT_FI3 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
A | ALA575 | |
B | ASN659 | |
B | ARG718 | |
B | MET732 | |
A | TYR605 | |
A | TYR653 | |
A | ASN659 | |
A | ARG718 | |
A | MET732 | |
B | ALA575 | |
B | TYR605 | |
B | TYR653 | |
Chain | Residue | Details |
A | ASP519 | |
B | ASP519 | |
Chain | Residue | Details |
A | ASP554 | |
A | ASP674 | |
A | ILE676 | |
B | ASP554 | |
B | ASP674 | |
B | ILE676 | |
Chain | Residue | Details |
A | ARG744 | |
A | PRO745 | |
B | ARG744 | |
B | PRO745 | |