6MU4

Bst DNA polymerase I FANA/DNA binary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0004518	molecular_function	nuclease activity
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0046872	molecular_function	metal ion binding
A	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MPD A 901

Chain	Residue
A	TYR714
A	GLY715
A	ARG789
T	GFL4
T	UF25

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MPD A 902

Chain	Residue
A	ARG677
A	ALA300
A	PHE301
A	ARG343
A	ARG449

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MPD A 903

Chain	Residue
A	GLY715
A	ILE716
A	ILE736
A	ARG789

---

site_id	AC4
Number of Residues	2
Details	binding site for residue SO4 A 904

Chain	Residue
A	ARG702
A	LYS706

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 905

Chain	Residue
A	ARG343
A	ARG677
A	LYS684

---

site_id	AC6
Number of Residues	3
Details	binding site for residue MG A 906

Chain	Residue
A	GLU658
A	ASP830
A	HOH1123

---

site_id	AC7
Number of Residues	8
Details	binding site for residues GFL T 4 and UF2 T 5

Chain	Residue
A	ILE716
A	SER717
A	GLY720
A	PHE786
A	ARG789
A	MPD901
P	DT11
T	A5L6

---

site_id	AC8
Number of Residues	9
Details	binding site for residues UF2 T 5 and A5L T 6

Chain	Residue
A	PHE786
A	MPD901
P	DG9
P	DT10
P	DT11
T	GFL4
T	CFL7
T	HOH102
T	HOH120

---

site_id	AC9
Number of Residues	10
Details	binding site for residues A5L T 6 and CFL T 7

Chain	Residue
A	LEU610
A	SER617
P	DC8
P	DG9
P	DT10
P	DT11
T	UF25
T	GFL8
T	HOH102
T	HOH120

---

site_id	AD1
Number of Residues	11
Details	binding site for residues CFL T 7 and GFL T 8

Chain	Residue
A	LEU610
A	SER617
A	THR619
P	DA7
P	DC8
P	DG9
P	DT10
T	A5L6
T	UF29
T	HOH103
T	HOH105

---

site_id	AD2
Number of Residues	13
Details	binding site for residues GFL T 8 and UF2 T 9

Chain	Residue
A	LEU610
A	SER617
A	THR619
A	GLU620
P	DA7
P	DC8
P	DG9
T	CFL7
T	GFL10
T	HOH103
T	HOH105
T	HOH110
T	HOH118

---

site_id	AD3
Number of Residues	19
Details	binding site for residues UF2 T 9 and GFL T 10

Chain	Residue
A	SER585
A	THR586
A	GLY590
A	LYS593
A	THR619
A	GLU620
P	DC6
P	DA7
T	GFL8
T	A5L11
T	HOH104
T	HOH107
T	HOH108
T	HOH109
T	HOH110
T	HOH112
T	HOH113
T	HOH115
T	HOH118

---

site_id	AD4
Number of Residues	19
Details	binding site for residues GFL T 10 and A5L T 11

Chain	Residue
P	DA7
T	UF29
T	UF212
T	HOH104
T	HOH107
T	HOH108
T	HOH109
T	HOH112
T	HOH113
T	HOH115
T	HOH116
T	HOH119
A	SER585
A	THR586
A	GLY590
A	LYS593
P	DA4
P	DT5
P	DC6

---

site_id	AD5
Number of Residues	12
Details	binding site for residues A5L T 11 and UF2 T 12

Chain	Residue
A	ASN527
A	ASN529
A	SER530
A	SER585
P	DG3
P	DA4
P	DT5
P	DC6
T	GFL10
T	CFL13
T	HOH116
T	HOH119

---

site_id	AD6
Number of Residues	10
Details	binding site for residues UF2 T 12 and CFL T 13

Chain	Residue
A	ASN527
A	ASN529
A	SER530
A	GLN533
P	DC2
P	DG3
P	DA4
T	A5L11
T	GFL14
T	HOH111

---

site_id	AD7
Number of Residues	9
Details	binding site for residues CFL T 13 and GFL T 14

Chain	Residue
A	SER530
A	GLN533
P	DG1
P	DC2
P	DG3
P	DA4
T	UF212
T	CFL15
T	HOH111

---

site_id	AD8
Number of Residues	7
Details	binding site for residues GFL T 14 and CFL T 15

Chain	Residue
P	DG1
P	DC2
P	DG3
T	CFL13
T	A5L16
T	HOH117
T	HOH123

---

site_id	AD9
Number of Residues	7
Details	binding site for residues CFL T 15 and A5L T 16

Chain	Residue
P	DG1
T	GFL14
T	HOH101
T	HOH106
T	HOH114
T	HOH117
T	HOH123

---

Functional Information from PROSITE/UniProt

site_id	PS00447
Number of Residues	20
Details	DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnFGivYgiSdygL

Chain	Residue	Details
A	ARG702-LEU721

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