6MRD

ADP-bound human mitochondrial Hsp60-Hsp10 half-football complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001530	molecular_function	lipopolysaccharide binding
A	0002039	molecular_function	p53 binding
A	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
A	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
A	0003688	molecular_function	DNA replication origin binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005759	cellular_component	mitochondrial matrix
A	0005769	cellular_component	early endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005905	cellular_component	clathrin-coated pit
A	0006457	biological_process	protein folding
A	0006458	biological_process	'de novo' protein folding
A	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
A	0006986	biological_process	response to unfolded protein
A	0008035	molecular_function	high-density lipoprotein particle binding
A	0008637	biological_process	apoptotic mitochondrial changes
A	0009409	biological_process	response to cold
A	0009986	cellular_component	cell surface
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019899	molecular_function	enzyme binding
A	0030135	cellular_component	coated vesicle
A	0030141	cellular_component	secretory granule
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032727	biological_process	positive regulation of interferon-alpha production
A	0032729	biological_process	positive regulation of type II interferon production
A	0032733	biological_process	positive regulation of interleukin-10 production
A	0032735	biological_process	positive regulation of interleukin-12 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032991	cellular_component	protein-containing complex
A	0034185	molecular_function	apolipoprotein binding
A	0034186	molecular_function	apolipoprotein A-I binding
A	0034514	biological_process	mitochondrial unfolded protein response
A	0042026	biological_process	protein refolding
A	0042100	biological_process	B cell proliferation
A	0042110	biological_process	T cell activation
A	0042113	biological_process	B cell activation
A	0043032	biological_process	positive regulation of macrophage activation
A	0043065	biological_process	positive regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0044406	biological_process	adhesion of symbiont to host
A	0045041	biological_process	protein import into mitochondrial intermembrane space
A	0046696	cellular_component	lipopolysaccharide receptor complex
A	0048291	biological_process	isotype switching to IgG isotypes
A	0050821	biological_process	protein stabilization
A	0050870	biological_process	positive regulation of T cell activation
A	0051082	molecular_function	unfolded protein binding
A	0051087	molecular_function	protein-folding chaperone binding
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0051604	biological_process	protein maturation
A	0051702	biological_process	biological process involved in interaction with symbiont
A	0070062	cellular_component	extracellular exosome
A	0097225	cellular_component	sperm midpiece
A	0097524	cellular_component	sperm plasma membrane
A	0098761	biological_process	cellular response to interleukin-7
A	0140494	cellular_component	migrasome
A	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0001530	molecular_function	lipopolysaccharide binding
B	0002039	molecular_function	p53 binding
B	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
B	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
B	0003688	molecular_function	DNA replication origin binding
B	0003697	molecular_function	single-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0003725	molecular_function	double-stranded RNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005759	cellular_component	mitochondrial matrix
B	0005769	cellular_component	early endosome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005905	cellular_component	clathrin-coated pit
B	0006457	biological_process	protein folding
B	0006458	biological_process	'de novo' protein folding
B	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
B	0006986	biological_process	response to unfolded protein
B	0008035	molecular_function	high-density lipoprotein particle binding
B	0008637	biological_process	apoptotic mitochondrial changes
B	0009409	biological_process	response to cold
B	0009986	cellular_component	cell surface
B	0016020	cellular_component	membrane
B	0016853	molecular_function	isomerase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0019899	molecular_function	enzyme binding
B	0030135	cellular_component	coated vesicle
B	0030141	cellular_component	secretory granule
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032727	biological_process	positive regulation of interferon-alpha production
B	0032729	biological_process	positive regulation of type II interferon production
B	0032733	biological_process	positive regulation of interleukin-10 production
B	0032735	biological_process	positive regulation of interleukin-12 production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032991	cellular_component	protein-containing complex
B	0034185	molecular_function	apolipoprotein binding
B	0034186	molecular_function	apolipoprotein A-I binding
B	0034514	biological_process	mitochondrial unfolded protein response
B	0042026	biological_process	protein refolding
B	0042100	biological_process	B cell proliferation
B	0042110	biological_process	T cell activation
B	0042113	biological_process	B cell activation
B	0043032	biological_process	positive regulation of macrophage activation
B	0043065	biological_process	positive regulation of apoptotic process
B	0043066	biological_process	negative regulation of apoptotic process
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0044406	biological_process	adhesion of symbiont to host
B	0045041	biological_process	protein import into mitochondrial intermembrane space
B	0046696	cellular_component	lipopolysaccharide receptor complex
B	0048291	biological_process	isotype switching to IgG isotypes
B	0050821	biological_process	protein stabilization
B	0050870	biological_process	positive regulation of T cell activation
B	0051082	molecular_function	unfolded protein binding
B	0051087	molecular_function	protein-folding chaperone binding
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0051604	biological_process	protein maturation
B	0051702	biological_process	biological process involved in interaction with symbiont
B	0070062	cellular_component	extracellular exosome
B	0097225	cellular_component	sperm midpiece
B	0097524	cellular_component	sperm plasma membrane
B	0098761	biological_process	cellular response to interleukin-7
B	0140494	cellular_component	migrasome
B	0140662	molecular_function	ATP-dependent protein folding chaperone
C	0001530	molecular_function	lipopolysaccharide binding
C	0002039	molecular_function	p53 binding
C	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
C	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
C	0003688	molecular_function	DNA replication origin binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003723	molecular_function	RNA binding
C	0003725	molecular_function	double-stranded RNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005759	cellular_component	mitochondrial matrix
C	0005769	cellular_component	early endosome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0005905	cellular_component	clathrin-coated pit
C	0006457	biological_process	protein folding
C	0006458	biological_process	'de novo' protein folding
C	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
C	0006986	biological_process	response to unfolded protein
C	0008035	molecular_function	high-density lipoprotein particle binding
C	0008637	biological_process	apoptotic mitochondrial changes
C	0009409	biological_process	response to cold
C	0009986	cellular_component	cell surface
C	0016020	cellular_component	membrane
C	0016853	molecular_function	isomerase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019899	molecular_function	enzyme binding
C	0030135	cellular_component	coated vesicle
C	0030141	cellular_component	secretory granule
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032727	biological_process	positive regulation of interferon-alpha production
C	0032729	biological_process	positive regulation of type II interferon production
C	0032733	biological_process	positive regulation of interleukin-10 production
C	0032735	biological_process	positive regulation of interleukin-12 production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0032991	cellular_component	protein-containing complex
C	0034185	molecular_function	apolipoprotein binding
C	0034186	molecular_function	apolipoprotein A-I binding
C	0034514	biological_process	mitochondrial unfolded protein response
C	0042026	biological_process	protein refolding
C	0042100	biological_process	B cell proliferation
C	0042110	biological_process	T cell activation
C	0042113	biological_process	B cell activation
C	0043032	biological_process	positive regulation of macrophage activation
C	0043065	biological_process	positive regulation of apoptotic process
C	0043066	biological_process	negative regulation of apoptotic process
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0044406	biological_process	adhesion of symbiont to host
C	0045041	biological_process	protein import into mitochondrial intermembrane space
C	0046696	cellular_component	lipopolysaccharide receptor complex
C	0048291	biological_process	isotype switching to IgG isotypes
C	0050821	biological_process	protein stabilization
C	0050870	biological_process	positive regulation of T cell activation
C	0051082	molecular_function	unfolded protein binding
C	0051087	molecular_function	protein-folding chaperone binding
C	0051131	biological_process	chaperone-mediated protein complex assembly
C	0051604	biological_process	protein maturation
C	0051702	biological_process	biological process involved in interaction with symbiont
C	0070062	cellular_component	extracellular exosome
C	0097225	cellular_component	sperm midpiece
C	0097524	cellular_component	sperm plasma membrane
C	0098761	biological_process	cellular response to interleukin-7
C	0140494	cellular_component	migrasome
C	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0001530	molecular_function	lipopolysaccharide binding
D	0002039	molecular_function	p53 binding
D	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
D	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
D	0003688	molecular_function	DNA replication origin binding
D	0003697	molecular_function	single-stranded DNA binding
D	0003723	molecular_function	RNA binding
D	0003725	molecular_function	double-stranded RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005759	cellular_component	mitochondrial matrix
D	0005769	cellular_component	early endosome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005905	cellular_component	clathrin-coated pit
D	0006457	biological_process	protein folding
D	0006458	biological_process	'de novo' protein folding
D	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
D	0006986	biological_process	response to unfolded protein
D	0008035	molecular_function	high-density lipoprotein particle binding
D	0008637	biological_process	apoptotic mitochondrial changes
D	0009409	biological_process	response to cold
D	0009986	cellular_component	cell surface
D	0016020	cellular_component	membrane
D	0016853	molecular_function	isomerase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0019899	molecular_function	enzyme binding
D	0030135	cellular_component	coated vesicle
D	0030141	cellular_component	secretory granule
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0032727	biological_process	positive regulation of interferon-alpha production
D	0032729	biological_process	positive regulation of type II interferon production
D	0032733	biological_process	positive regulation of interleukin-10 production
D	0032735	biological_process	positive regulation of interleukin-12 production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0032991	cellular_component	protein-containing complex
D	0034185	molecular_function	apolipoprotein binding
D	0034186	molecular_function	apolipoprotein A-I binding
D	0034514	biological_process	mitochondrial unfolded protein response
D	0042026	biological_process	protein refolding
D	0042100	biological_process	B cell proliferation
D	0042110	biological_process	T cell activation
D	0042113	biological_process	B cell activation
D	0043032	biological_process	positive regulation of macrophage activation
D	0043065	biological_process	positive regulation of apoptotic process
D	0043066	biological_process	negative regulation of apoptotic process
D	0043231	cellular_component	intracellular membrane-bounded organelle
D	0044406	biological_process	adhesion of symbiont to host
D	0045041	biological_process	protein import into mitochondrial intermembrane space
D	0046696	cellular_component	lipopolysaccharide receptor complex
D	0048291	biological_process	isotype switching to IgG isotypes
D	0050821	biological_process	protein stabilization
D	0050870	biological_process	positive regulation of T cell activation
D	0051082	molecular_function	unfolded protein binding
D	0051087	molecular_function	protein-folding chaperone binding
D	0051131	biological_process	chaperone-mediated protein complex assembly
D	0051604	biological_process	protein maturation
D	0051702	biological_process	biological process involved in interaction with symbiont
D	0070062	cellular_component	extracellular exosome
D	0097225	cellular_component	sperm midpiece
D	0097524	cellular_component	sperm plasma membrane
D	0098761	biological_process	cellular response to interleukin-7
D	0140494	cellular_component	migrasome
D	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0001530	molecular_function	lipopolysaccharide binding
E	0002039	molecular_function	p53 binding
E	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
E	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
E	0003688	molecular_function	DNA replication origin binding
E	0003697	molecular_function	single-stranded DNA binding
E	0003723	molecular_function	RNA binding
E	0003725	molecular_function	double-stranded RNA binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005615	cellular_component	extracellular space
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005759	cellular_component	mitochondrial matrix
E	0005769	cellular_component	early endosome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005905	cellular_component	clathrin-coated pit
E	0006457	biological_process	protein folding
E	0006458	biological_process	'de novo' protein folding
E	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
E	0006986	biological_process	response to unfolded protein
E	0008035	molecular_function	high-density lipoprotein particle binding
E	0008637	biological_process	apoptotic mitochondrial changes
E	0009409	biological_process	response to cold
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019899	molecular_function	enzyme binding
E	0030135	cellular_component	coated vesicle
E	0030141	cellular_component	secretory granule
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032727	biological_process	positive regulation of interferon-alpha production
E	0032729	biological_process	positive regulation of type II interferon production
E	0032733	biological_process	positive regulation of interleukin-10 production
E	0032735	biological_process	positive regulation of interleukin-12 production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0032991	cellular_component	protein-containing complex
E	0034185	molecular_function	apolipoprotein binding
E	0034186	molecular_function	apolipoprotein A-I binding
E	0034514	biological_process	mitochondrial unfolded protein response
E	0042026	biological_process	protein refolding
E	0042100	biological_process	B cell proliferation
E	0042110	biological_process	T cell activation
E	0042113	biological_process	B cell activation
E	0043032	biological_process	positive regulation of macrophage activation
E	0043065	biological_process	positive regulation of apoptotic process
E	0043066	biological_process	negative regulation of apoptotic process
E	0043231	cellular_component	intracellular membrane-bounded organelle
E	0044406	biological_process	adhesion of symbiont to host
E	0045041	biological_process	protein import into mitochondrial intermembrane space
E	0046696	cellular_component	lipopolysaccharide receptor complex
E	0048291	biological_process	isotype switching to IgG isotypes
E	0050821	biological_process	protein stabilization
E	0050870	biological_process	positive regulation of T cell activation
E	0051082	molecular_function	unfolded protein binding
E	0051087	molecular_function	protein-folding chaperone binding
E	0051131	biological_process	chaperone-mediated protein complex assembly
E	0051604	biological_process	protein maturation
E	0051702	biological_process	biological process involved in interaction with symbiont
E	0070062	cellular_component	extracellular exosome
E	0097225	cellular_component	sperm midpiece
E	0097524	cellular_component	sperm plasma membrane
E	0098761	biological_process	cellular response to interleukin-7
E	0140494	cellular_component	migrasome
E	0140662	molecular_function	ATP-dependent protein folding chaperone
F	0001530	molecular_function	lipopolysaccharide binding
F	0002039	molecular_function	p53 binding
F	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
F	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
F	0003688	molecular_function	DNA replication origin binding
F	0003697	molecular_function	single-stranded DNA binding
F	0003723	molecular_function	RNA binding
F	0003725	molecular_function	double-stranded RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005759	cellular_component	mitochondrial matrix
F	0005769	cellular_component	early endosome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005905	cellular_component	clathrin-coated pit
F	0006457	biological_process	protein folding
F	0006458	biological_process	'de novo' protein folding
F	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
F	0006986	biological_process	response to unfolded protein
F	0008035	molecular_function	high-density lipoprotein particle binding
F	0008637	biological_process	apoptotic mitochondrial changes
F	0009409	biological_process	response to cold
F	0009986	cellular_component	cell surface
F	0016020	cellular_component	membrane
F	0016853	molecular_function	isomerase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0019899	molecular_function	enzyme binding
F	0030135	cellular_component	coated vesicle
F	0030141	cellular_component	secretory granule
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032727	biological_process	positive regulation of interferon-alpha production
F	0032729	biological_process	positive regulation of type II interferon production
F	0032733	biological_process	positive regulation of interleukin-10 production
F	0032735	biological_process	positive regulation of interleukin-12 production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0032991	cellular_component	protein-containing complex
F	0034185	molecular_function	apolipoprotein binding
F	0034186	molecular_function	apolipoprotein A-I binding
F	0034514	biological_process	mitochondrial unfolded protein response
F	0042026	biological_process	protein refolding
F	0042100	biological_process	B cell proliferation
F	0042110	biological_process	T cell activation
F	0042113	biological_process	B cell activation
F	0043032	biological_process	positive regulation of macrophage activation
F	0043065	biological_process	positive regulation of apoptotic process
F	0043066	biological_process	negative regulation of apoptotic process
F	0043231	cellular_component	intracellular membrane-bounded organelle
F	0044406	biological_process	adhesion of symbiont to host
F	0045041	biological_process	protein import into mitochondrial intermembrane space
F	0046696	cellular_component	lipopolysaccharide receptor complex
F	0048291	biological_process	isotype switching to IgG isotypes
F	0050821	biological_process	protein stabilization
F	0050870	biological_process	positive regulation of T cell activation
F	0051082	molecular_function	unfolded protein binding
F	0051087	molecular_function	protein-folding chaperone binding
F	0051131	biological_process	chaperone-mediated protein complex assembly
F	0051604	biological_process	protein maturation
F	0051702	biological_process	biological process involved in interaction with symbiont
F	0070062	cellular_component	extracellular exosome
F	0097225	cellular_component	sperm midpiece
F	0097524	cellular_component	sperm plasma membrane
F	0098761	biological_process	cellular response to interleukin-7
F	0140494	cellular_component	migrasome
F	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0001530	molecular_function	lipopolysaccharide binding
G	0002039	molecular_function	p53 binding
G	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
G	0002842	biological_process	positive regulation of T cell mediated immune response to tumor cell
G	0003688	molecular_function	DNA replication origin binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003723	molecular_function	RNA binding
G	0003725	molecular_function	double-stranded RNA binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005615	cellular_component	extracellular space
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005759	cellular_component	mitochondrial matrix
G	0005769	cellular_component	early endosome
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0005905	cellular_component	clathrin-coated pit
G	0006457	biological_process	protein folding
G	0006458	biological_process	'de novo' protein folding
G	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
G	0006986	biological_process	response to unfolded protein
G	0008035	molecular_function	high-density lipoprotein particle binding
G	0008637	biological_process	apoptotic mitochondrial changes
G	0009409	biological_process	response to cold
G	0009986	cellular_component	cell surface
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019899	molecular_function	enzyme binding
G	0030135	cellular_component	coated vesicle
G	0030141	cellular_component	secretory granule
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032727	biological_process	positive regulation of interferon-alpha production
G	0032729	biological_process	positive regulation of type II interferon production
G	0032733	biological_process	positive regulation of interleukin-10 production
G	0032735	biological_process	positive regulation of interleukin-12 production
G	0032755	biological_process	positive regulation of interleukin-6 production
G	0032991	cellular_component	protein-containing complex
G	0034185	molecular_function	apolipoprotein binding
G	0034186	molecular_function	apolipoprotein A-I binding
G	0034514	biological_process	mitochondrial unfolded protein response
G	0042026	biological_process	protein refolding
G	0042100	biological_process	B cell proliferation
G	0042110	biological_process	T cell activation
G	0042113	biological_process	B cell activation
G	0043032	biological_process	positive regulation of macrophage activation
G	0043065	biological_process	positive regulation of apoptotic process
G	0043066	biological_process	negative regulation of apoptotic process
G	0043231	cellular_component	intracellular membrane-bounded organelle
G	0044406	biological_process	adhesion of symbiont to host
G	0045041	biological_process	protein import into mitochondrial intermembrane space
G	0046696	cellular_component	lipopolysaccharide receptor complex
G	0048291	biological_process	isotype switching to IgG isotypes
G	0050821	biological_process	protein stabilization
G	0050870	biological_process	positive regulation of T cell activation
G	0051082	molecular_function	unfolded protein binding
G	0051087	molecular_function	protein-folding chaperone binding
G	0051131	biological_process	chaperone-mediated protein complex assembly
G	0051604	biological_process	protein maturation
G	0051702	biological_process	biological process involved in interaction with symbiont
G	0070062	cellular_component	extracellular exosome
G	0097225	cellular_component	sperm midpiece
G	0097524	cellular_component	sperm plasma membrane
G	0098761	biological_process	cellular response to interleukin-7
G	0140494	cellular_component	migrasome
G	0140662	molecular_function	ATP-dependent protein folding chaperone
O	0001649	biological_process	osteoblast differentiation
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005739	cellular_component	mitochondrion
O	0005759	cellular_component	mitochondrial matrix
O	0006457	biological_process	protein folding
O	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
O	0006986	biological_process	response to unfolded protein
O	0016020	cellular_component	membrane
O	0044183	molecular_function	protein folding chaperone
O	0046872	molecular_function	metal ion binding
O	0051082	molecular_function	unfolded protein binding
O	0051085	biological_process	chaperone cofactor-dependent protein refolding
O	0051087	molecular_function	protein-folding chaperone binding
O	0070062	cellular_component	extracellular exosome
P	0001649	biological_process	osteoblast differentiation
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005739	cellular_component	mitochondrion
P	0005759	cellular_component	mitochondrial matrix
P	0006457	biological_process	protein folding
P	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
P	0006986	biological_process	response to unfolded protein
P	0016020	cellular_component	membrane
P	0044183	molecular_function	protein folding chaperone
P	0046872	molecular_function	metal ion binding
P	0051082	molecular_function	unfolded protein binding
P	0051085	biological_process	chaperone cofactor-dependent protein refolding
P	0051087	molecular_function	protein-folding chaperone binding
P	0070062	cellular_component	extracellular exosome
Q	0001649	biological_process	osteoblast differentiation
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005739	cellular_component	mitochondrion
Q	0005759	cellular_component	mitochondrial matrix
Q	0006457	biological_process	protein folding
Q	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
Q	0006986	biological_process	response to unfolded protein
Q	0016020	cellular_component	membrane
Q	0044183	molecular_function	protein folding chaperone
Q	0046872	molecular_function	metal ion binding
Q	0051082	molecular_function	unfolded protein binding
Q	0051085	biological_process	chaperone cofactor-dependent protein refolding
Q	0051087	molecular_function	protein-folding chaperone binding
Q	0070062	cellular_component	extracellular exosome
R	0001649	biological_process	osteoblast differentiation
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005524	molecular_function	ATP binding
R	0005739	cellular_component	mitochondrion
R	0005759	cellular_component	mitochondrial matrix
R	0006457	biological_process	protein folding
R	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
R	0006986	biological_process	response to unfolded protein
R	0016020	cellular_component	membrane
R	0044183	molecular_function	protein folding chaperone
R	0046872	molecular_function	metal ion binding
R	0051082	molecular_function	unfolded protein binding
R	0051085	biological_process	chaperone cofactor-dependent protein refolding
R	0051087	molecular_function	protein-folding chaperone binding
R	0070062	cellular_component	extracellular exosome
S	0001649	biological_process	osteoblast differentiation
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005739	cellular_component	mitochondrion
S	0005759	cellular_component	mitochondrial matrix
S	0006457	biological_process	protein folding
S	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
S	0006986	biological_process	response to unfolded protein
S	0016020	cellular_component	membrane
S	0044183	molecular_function	protein folding chaperone
S	0046872	molecular_function	metal ion binding
S	0051082	molecular_function	unfolded protein binding
S	0051085	biological_process	chaperone cofactor-dependent protein refolding
S	0051087	molecular_function	protein-folding chaperone binding
S	0070062	cellular_component	extracellular exosome
T	0001649	biological_process	osteoblast differentiation
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005739	cellular_component	mitochondrion
T	0005759	cellular_component	mitochondrial matrix
T	0006457	biological_process	protein folding
T	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
T	0006986	biological_process	response to unfolded protein
T	0016020	cellular_component	membrane
T	0044183	molecular_function	protein folding chaperone
T	0046872	molecular_function	metal ion binding
T	0051082	molecular_function	unfolded protein binding
T	0051085	biological_process	chaperone cofactor-dependent protein refolding
T	0051087	molecular_function	protein-folding chaperone binding
T	0070062	cellular_component	extracellular exosome
U	0001649	biological_process	osteoblast differentiation
U	0003723	molecular_function	RNA binding
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005739	cellular_component	mitochondrion
U	0005759	cellular_component	mitochondrial matrix
U	0006457	biological_process	protein folding
U	0006919	biological_process	activation of cysteine-type endopeptidase activity involved in apoptotic process
U	0006986	biological_process	response to unfolded protein
U	0016020	cellular_component	membrane
U	0044183	molecular_function	protein folding chaperone
U	0046872	molecular_function	metal ion binding
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0051087	molecular_function	protein-folding chaperone binding
U	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue ADP A 601

Chain	Residue
A	THR30
A	THR91
A	GLY415
A	GLY416
A	ASP480
A	ILE494
A	ASP496
A	MG602
A	MET31
A	GLY32
A	PRO33
A	LYS51
A	ASP87
A	GLY88
A	THR89
A	THR90

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MG A 602

Chain	Residue
A	ASP87
A	ADP601

---

site_id	AC3
Number of Residues	17
Details	binding site for residue ADP G 601

Chain	Residue
G	THR30
G	MET31
G	GLY32
G	PRO33
G	LYS51
G	ASP87
G	GLY88
G	THR89
G	THR90
G	THR91
G	GLY415
G	GLY416
G	GLY417
G	ASP480
G	ILE494
G	ASP496
G	MG602

---

site_id	AC4
Number of Residues	2
Details	binding site for residue MG G 602

Chain	Residue
G	ASP87
G	ADP601

---

site_id	AC5
Number of Residues	14
Details	binding site for residue ADP F 601

Chain	Residue
F	GLY32
F	PRO33
F	ASP87
F	GLY88
F	THR91
F	GLY415
F	GLY416
F	TYR479
F	ASP480
F	ALA481
F	ILE494
F	ASP496
F	VAL500
F	MG602

---

site_id	AC6
Number of Residues	2
Details	binding site for residue MG F 602

Chain	Residue
F	THR90
F	ADP601

---

site_id	AC7
Number of Residues	17
Details	binding site for residue ADP E 601

Chain	Residue
E	THR30
E	MET31
E	GLY32
E	PRO33
E	LYS51
E	ASP87
E	GLY88
E	THR89
E	THR90
E	THR91
E	GLY415
E	GLY416
E	GLY417
E	ASP480
E	ILE494
E	ASP496
E	MG602

---

site_id	AC8
Number of Residues	2
Details	binding site for residue MG E 602

Chain	Residue
E	ASP87
E	ADP601

---

site_id	AC9
Number of Residues	16
Details	binding site for residue ADP D 601

Chain	Residue
D	THR30
D	MET31
D	GLY32
D	PRO33
D	LYS51
D	ASP87
D	GLY88
D	THR89
D	THR90
D	THR91
D	GLY415
D	GLY416
D	ASP480
D	ILE494
D	ASP496
D	MG602

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MG D 602

Chain	Residue
D	ASP87
D	ADP601

---

site_id	AD2
Number of Residues	17
Details	binding site for residue ADP C 601

Chain	Residue
C	THR91
C	GLY415
C	GLY416
C	GLY417
C	ASP480
C	ILE494
C	ASP496
C	MG602
C	THR30
C	MET31
C	GLY32
C	PRO33
C	LYS51
C	ASP87
C	GLY88
C	THR89
C	THR90

---

site_id	AD3
Number of Residues	1
Details	binding site for residue MG C 602

Chain	Residue
C	ADP601

---

site_id	AD4
Number of Residues	17
Details	binding site for residue ADP B 601

Chain	Residue
B	THR30
B	MET31
B	GLY32
B	PRO33
B	LYS51
B	ASP87
B	GLY88
B	THR89
B	THR90
B	THR91
B	GLY415
B	GLY416
B	GLY417
B	ASP480
B	ILE494
B	ASP496
B	MG602

---

site_id	AD5
Number of Residues	2
Details	binding site for residue MG B 602

Chain	Residue
B	ASP87
B	ADP601

---

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGIVlGGG

Chain	Residue	Details
A	ALA406-GLY417

---

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. FlPLfDRVLVErsaaetvtkGgIML

Chain	Residue	Details
O	PHE9-LEU33

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
O	LYS8
F	ASP87
F	GLY416
F	ASP496
E	LYS51
E	ASP87
E	GLY416
E	ASP496
D	LYS51
D	ASP87
D	GLY416
U	LYS8
D	ASP496
C	LYS51
C	ASP87
C	GLY416
C	ASP496
B	LYS51
B	ASP87
B	GLY416
B	ASP496
T	LYS8
S	LYS8
R	LYS8
Q	LYS8
P	LYS8
G	ASP496
F	LYS51

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
O	LYS28
D	LYS277
C	LYS7
C	LYS277
B	LYS7
B	LYS277
U	LYS28
T	LYS28
S	LYS28
R	LYS28
Q	LYS28
P	LYS28
E	LYS277
D	LYS7

---

site_id	SWS_FT_FI3
Number of Residues	49
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q64433

Chain	Residue	Details
O	LYS40
U	LYS56
U	LYS66
U	LYS70
U	LYS80
U	LYS86
T	LYS40
T	LYS54
T	LYS56
T	LYS66
T	LYS70
O	LYS54
T	LYS80
T	LYS86
S	LYS40
S	LYS54
S	LYS56
S	LYS66
S	LYS70
S	LYS80
S	LYS86
R	LYS40
O	LYS56
R	LYS54
R	LYS56
R	LYS66
R	LYS70
R	LYS80
R	LYS86
Q	LYS40
Q	LYS54
Q	LYS56
Q	LYS66
O	LYS66
Q	LYS70
Q	LYS80
Q	LYS86
P	LYS40
P	LYS54
P	LYS56
P	LYS66
P	LYS70
P	LYS80
P	LYS86
O	LYS70
O	LYS80
O	LYS86
U	LYS40
U	LYS54

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
O	THR79
U	THR79
T	THR79
S	THR79
R	THR79
Q	THR79
P	THR79

---

site_id	SWS_FT_FI5
Number of Residues	7
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
O	LYS99
G	LYS63
G	LYS67
G	LYS132
G	LYS225
G	LYS268
G	LYS290
G	LYS365
F	LYS51
F	LYS63
F	LYS67
U	LYS99
F	LYS132
F	LYS225
F	LYS268
F	LYS290
F	LYS365
E	LYS51
E	LYS63
E	LYS67
E	LYS132
E	LYS225
T	LYS99
E	LYS268
E	LYS290
E	LYS365
D	LYS51
D	LYS63
D	LYS67
D	LYS132
D	LYS225
D	LYS268
D	LYS290
S	LYS99
D	LYS365
C	LYS51
C	LYS63
C	LYS67
C	LYS132
C	LYS225
C	LYS268
C	LYS290
C	LYS365
B	LYS51
R	LYS99
B	LYS63
B	LYS67
B	LYS132
B	LYS225
B	LYS268
B	LYS290
B	LYS365
Q	LYS99
P	LYS99
A	LYS365
G	LYS51

---

site_id	SWS_FT_FI6
Number of Residues	84
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
A	LYS58
A	LYS328
A	LYS372
A	LYS457
G	LYS58
G	LYS101
G	LYS109
G	LYS167
G	LYS178
G	LYS181
G	LYS194
A	LYS101
G	LYS212
G	LYS226
G	LYS328
G	LYS372
G	LYS457
F	LYS58
F	LYS101
F	LYS109
F	LYS167
F	LYS178
A	LYS109
F	LYS181
F	LYS194
F	LYS212
F	LYS226
F	LYS328
F	LYS372
F	LYS457
E	LYS58
E	LYS101
E	LYS109
A	LYS167
E	LYS167
E	LYS178
E	LYS181
E	LYS194
E	LYS212
E	LYS226
E	LYS328
E	LYS372
E	LYS457
D	LYS58
A	LYS178
D	LYS101
D	LYS109
D	LYS167
D	LYS178
D	LYS181
D	LYS194
D	LYS212
D	LYS226
D	LYS328
D	LYS372
A	LYS181
D	LYS457
C	LYS58
C	LYS101
C	LYS109
C	LYS167
C	LYS178
C	LYS181
C	LYS194
C	LYS212
C	LYS226
A	LYS194
C	LYS328
C	LYS372
C	LYS457
B	LYS58
B	LYS101
B	LYS109
B	LYS167
B	LYS178
B	LYS181
B	LYS194
A	LYS212
B	LYS212
B	LYS226
B	LYS328
B	LYS372
B	LYS457
A	LYS226

---

site_id	SWS_FT_FI7
Number of Residues	7
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	TYR66
G	TYR66
F	TYR66
E	TYR66
D	TYR66
C	TYR66
B	TYR66

---

site_id	SWS_FT_FI8
Number of Residues	28
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS106
F	LYS245
F	LYS335
F	LYS445
E	LYS106
E	LYS245
E	LYS335
E	LYS445
D	LYS106
D	LYS245
D	LYS335
A	LYS245
D	LYS445
C	LYS106
C	LYS245
C	LYS335
C	LYS445
B	LYS106
B	LYS245
B	LYS335
B	LYS445
A	LYS335
A	LYS445
G	LYS106
G	LYS245
G	LYS335
G	LYS445
F	LYS106

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P63038

Chain	Residue	Details
A	SER386
G	SER386
F	SER386
E	SER386
D	SER386
C	SER386
B	SER386

---

site_id	SWS_FT_FI10
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER464
G	SER464
F	SER464
E	SER464
D	SER464
C	SER464
B	SER464

---

site_id	SWS_FT_FI11
Number of Residues	14
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS527
C	LYS527
B	LYS527
G	LYS527
F	LYS527
E	LYS527
D	LYS527

---