6MQL

Crystal Structure of GTPase Domain of Human Septin 12 Mutant T89M

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue GDP A 401

Chain	Residue
A	GLY59
A	GLY251
A	ARG266
A	MG402
A	HOH501
A	HOH505
A	HOH507
A	HOH512
A	HOH527
A	LEU60
A	GLY61
A	LYS62
A	SER63
A	THR64
A	ARG195
A	ASP197
A	VAL250

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 402

Chain	Residue
A	SER63
A	GDP401
A	HOH505
A	HOH512
A	HOH516
A	HOH540

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01056","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01056","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01056","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	19
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---