6MK5

Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS60021
Number of Residues	29
Details	HWTX_1 Huwentoxin-1 family signature. CLgAfrkCipdndkCCrpnlv.CsrlhRWC

Chain	Residue	Details
A	CYS2-CYS30

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Site: {"description":"Important for activity and sodium channel selectivity","evidences":[{"source":"PubMed","id":"25658507","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Site: {"description":"Important for activity","evidences":[{"source":"PubMed","id":"25658507","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phenylalanine amide","evidences":[{"source":"PubMed","id":"25658507","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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