6MIM

Crystal structure of AF9 YEATS domain Y78W mutant in complex with histone H3K9cr

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006355	biological_process	regulation of DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Region: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"5-glutamyl serotonin; alternate","evidences":[{"source":"PubMed","id":"30867594","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"source":"PubMed","id":"20228790","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5; alternate","evidences":[{"source":"UniProtKB","id":"P68433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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