Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue JQS A 500 |
| Chain | Residue |
| A | ALA49 |
| A | GLY342 |
| A | GLY343 |
| A | MET362 |
| A | GLY364 |
| A | SER365 |
| A | TYR388 |
| A | GLY390 |
| A | MET391 |
| A | GLY392 |
| A | GLU416 |
| A | MET51 |
| A | GLY417 |
| A | HOH626 |
| A | HOH633 |
| A | HOH640 |
| A | HOH670 |
| A | HOH679 |
| A | ASN280 |
| A | GLY305 |
| A | SER306 |
| A | ILE307 |
| A | CYS308 |
| A | THR310 |
| A | ASP341 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue K A 501 |
| Chain | Residue |
| A | GLY303 |
| A | GLY305 |
| A | CYS308 |
| A | GLU470 |
| A | SER471 |
| A | HIS472 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | PHE6 |
| A | GLU9 |
| A | LEU11 |
| A | THR322 |
| A | HOH651 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PGE A 503 |
| Chain | Residue |
| A | SER39 |
| A | ARG268 |
| A | PRO272 |
| A | SER273 |
| A | ASN275 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 504 |
| Chain | Residue |
| A | GLY10 |
| A | LEU11 |
| A | ASP15 |
| A | MET463 |
| A | HOH700 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 505 |
| Chain | Residue |
| A | PRO27 |
| A | HIS254 |
| A | GLU416 |
| A | ALA441 |
| A | GLY444 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | binding site for residue JQS B 500 |
| Chain | Residue |
| B | ALA49 |
| B | GLY305 |
| B | SER306 |
| B | ILE307 |
| B | CYS308 |
| B | THR310 |
| B | ASP341 |
| B | GLY342 |
| B | GLY343 |
| B | MET362 |
| B | GLY364 |
| B | SER365 |
| B | TYR388 |
| B | GLY390 |
| B | MET391 |
| B | GLY392 |
| B | GLU416 |
| B | GLY417 |
| B | HOH625 |
| B | HOH636 |
| B | HOH644 |
| B | HOH655 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue K B 501 |
| Chain | Residue |
| B | GLY303 |
| B | GLY305 |
| B | CYS308 |
| B | GLU470 |
| B | SER471 |
| B | HIS472 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | PHE6 |
| B | THR322 |
| B | HOH630 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 503 |
| Chain | Residue |
| B | SER39 |
| B | ARG268 |
| B | PRO272 |
| B | SER273 |
| B | ASN275 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 504 |
| Chain | Residue |
| B | GLY10 |
| B | LEU11 |
| B | MET463 |
| B | HOH661 |
| B | HOH666 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL298-THR310 | |
