6MDX
Mechanism of protease dependent DPC repair
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | ARG168 |
| A | TYR182 |
| A | ILE212 |
| A | FLC305 |
| A | HOH403 |
| A | HOH485 |
| A | HOH535 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PGE A 302 |
| Chain | Residue |
| A | LEU96 |
| A | ARG163 |
| A | ARG163 |
| A | THR73 |
| A | THR73 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 303 |
| Chain | Residue |
| A | HIS111 |
| A | HIS115 |
| A | HIS130 |
| A | FLC305 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 304 |
| Chain | Residue |
| A | CYS169 |
| A | CYS173 |
| A | HIS201 |
| A | CYS205 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue FLC A 305 |
| Chain | Residue |
| A | GLY77 |
| A | ILE78 |
| A | HIS111 |
| A | GLU112 |
| A | HIS115 |
| A | HIS130 |
| A | HIS153 |
| A | TRP166 |
| A | TYR182 |
| A | EDO301 |
| A | ZN303 |
| A | HOH417 |
| A | HOH427 |
| A | HOH436 |
| A | HOH472 |
| A | HOH535 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide MLZ A 184 and ARG A 185 |
| Chain | Residue |
| A | LEU74 |
| A | CYS75 |
| A | ARG163 |
| A | ARG164 |
| A | HIS165 |
| A | TRP166 |
| A | VAL183 |
| A | ALA186 |
| A | THR187 |
| A | ARG189 |
| A | GLU190 |
| A | PRO191 |
| A | ASP195 |
| A | TYR196 |
| A | TRP197 |
| A | HOH408 |
| A | HOH518 |
| A | HOH610 |
| D | DC1 |
| D | DC2 |
| D | HOH101 |
| D | HOH102 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TLLHEMIHAY |
| Chain | Residue | Details |
| A | THR108-TYR117 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27852435","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27871365","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27871366","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30893605","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30893605","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MDX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30893605","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MDX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
