Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004496 | molecular_function | mevalonate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004496 | molecular_function | mevalonate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MEV A 401 |
| Chain | Residue |
| A | TYR11 |
| A | HIS16 |
| A | GLY258 |
| A | HOH549 |
| A | HOH581 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue K A 402 |
| Chain | Residue |
| A | HIS59 |
| A | PRO60 |
| A | TYR61 |
| A | VAL62 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ARG51 |
| A | SER72 |
| A | PHE112 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | TYR140 |
| A | PHE144 |
| A | GLY145 |
| A | LYS155 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | SER3 |
| A | ARG34 |
| A | ARG36 |
| A | ASP83 |
| A | HOH591 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | LYS58 |
| A | GLU108 |
| A | LEU109 |
| A | HOH528 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | LEU39 |
| A | ASN40 |
| A | GLN48 |
| A | ASN76 |
| A | GLY77 |
| A | HOH523 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | GLY104 |
| A | ASN107 |
| A | GLU108 |
| A | LEU114 |
| A | LEU116 |
| A | ILE119 |
| A | LEU298 |
| A | VAL300 |
| A | HOH516 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 409 |
| Chain | Residue |
| A | PRO87 |
| A | GLY89 |
| A | SER90 |
| A | LEU92 |
| A | GLY93 |
| A | SER94 |
| A | SER95 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue MEV B 501 |
| Chain | Residue |
| B | GLU15 |
| B | HIS16 |
| B | VAL19 |
| B | GLY91 |
| B | VAL178 |
| B | HOH640 |
| B | HOH643 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue K B 502 |
| Chain | Residue |
| B | PRO87 |
| B | VAL88 |
| B | GLY89 |
| B | GLY93 |
| B | SER94 |
| B | GOL504 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| B | GLY213 |
| B | ASP214 |
| B | TYR215 |
| B | ALA216 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | VAL88 |
| B | GLY89 |
| B | GLY91 |
| B | LEU92 |
| B | GLY93 |
| B | SER94 |
| B | SER95 |
| B | K502 |
| B | HOH653 |
| B | HOH680 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 505 |
| Chain | Residue |
| B | VAL88 |
| B | ASP167 |
| B | GLY169 |
| B | VAL170 |
| B | PHE171 |
| B | GLY263 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| B | PHE56 |
| B | LYS129 |
| B | HOH611 |
| B | HOH672 |
| B | HOH697 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 507 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 508 |
| Chain | Residue |
| B | SER90 |
| B | SER172 |
| B | THR174 |
| B | ALA259 |
| B | GLY260 |
| B | HOH634 |
| B | HOH680 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 509 |
| Chain | Residue |
| B | GLU238 |
| B | HOH646 |
| B | HOH661 |
Functional Information from PROSITE/UniProt
| site_id | PS00627 |
| Number of Residues | 12 |
| Details | GHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. IPvGsGLGSSAA |
| Chain | Residue | Details |
| A | ILE86-ALA97 | |
