6MAM
Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| B | TYR194-HIS200 | |
| A | TYR212-HIS218 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | SITE: Involved in receptor recognition and/or post-binding events => ECO:0000255 |
| Chain | Residue | Details |
| G | LEU57 | |
| I | PHE88 | |
| I | LYS95 | |
| I | ILE170 | |
| K | LEU57 | |
| K | LEU63 | |
| K | ARG64 | |
| K | PHE88 | |
| K | LYS95 | |
| K | ILE170 | |
| G | LEU63 | |
| G | ARG64 | |
| G | PHE88 | |
| G | LYS95 | |
| G | ILE170 | |
| I | LEU57 | |
| I | LEU63 | |
| I | ARG64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000269|PubMed:9576958 |
| Chain | Residue | Details |
| G | ARG265 | |
| I | ARG265 | |
| K | ARG265 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 45 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255 |
| Chain | Residue | Details |
| G | ASN40 | |
| I | ASN40 | |
| I | ASN204 | |
| I | THR228 | |
| I | ALA238 | |
| G | ASN204 | |
| I | ILE257 | |
| G | THR228 | |
| K | ASN40 | |
| K | ASN204 | |
| K | THR228 | |
| K | ALA238 | |
| K | ILE257 | |
| G | ALA238 | |
| G | ILE257 |
