6M6S

Crystal structure of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3) C-terminal domain with 5'-ppp 12-mer dsRNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1201

Chain	Residue
A	CYS952
A	CYS955
A	CYS1007
A	CYS1010

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 1201

Chain	Residue
B	CYS952
B	CYS955
B	CYS1007
B	CYS1010

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site_id	AC3
Number of Residues	23
Details	binding site for Di-nucleotide GTP C 1 and G C 2

Chain	Residue
A	SER970
A	ASN971
A	LYS988
A	LYS990
A	SER992
A	LYS993
A	TYR994
A	ARG1016
A	TYR1018
A	GLN1027
A	HOH1301
C	C3
C	HOH102
C	HOH104
C	HOH107
C	HOH109
C	HOH112
C	HOH113
C	HOH117
D	G10
D	C11
D	C12
A	PHE969

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site_id	AC4
Number of Residues	23
Details	binding site for Di-nucleotide GTP C 1 and G C 2

Chain	Residue
A	PHE969
A	SER970
A	ASN971
A	LYS988
A	LYS990
A	SER992
A	LYS993
A	TYR994
A	ARG1016
A	TYR1018
A	GLN1027
A	HOH1301
C	C3
C	HOH102
C	HOH104
C	HOH107
C	HOH109
C	HOH112
C	HOH113
C	HOH117
D	G10
D	C11
D	C12

---

site_id	AC5
Number of Residues	22
Details	binding site for Di-nucleotide GTP D 1 and G D 2

Chain	Residue
B	PHE969
B	SER970
B	ASN971
B	LYS988
B	SER992
B	LYS993
B	TYR994
B	ARG1016
B	TYR1018
B	GLN1027
B	HOH1315
C	G10
C	C11
C	C12
D	C3
D	HOH101
D	HOH108
D	HOH109
D	HOH110
D	HOH111
D	HOH120
D	HOH124

---

site_id	AC6
Number of Residues	22
Details	binding site for Di-nucleotide GTP D 1 and G D 2

Chain	Residue
B	PHE969
B	SER970
B	ASN971
B	LYS988
B	SER992
B	LYS993
B	TYR994
B	ARG1016
B	TYR1018
B	GLN1027
B	HOH1315
C	G10
C	C11
C	C12
D	C3
D	HOH101
D	HOH108
D	HOH109
D	HOH110
D	HOH111
D	HOH120
D	HOH124

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