Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 0016579 | biological_process | protein deubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue EZF A 601 |
| Chain | Residue |
| A | ASP295 |
| A | LYS420 |
| A | ASP459 |
| A | ASN460 |
| A | HIS461 |
| A | TYR465 |
| A | TYR514 |
| A | HOH717 |
| A | VAL296 |
| A | GLN297 |
| A | GLN351 |
| A | LEU406 |
| A | MET407 |
| A | ARG408 |
| A | PHE409 |
| A | ASN418 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue EZF B 601 |
| Chain | Residue |
| B | ASP295 |
| B | VAL296 |
| B | GLN297 |
| B | GLN351 |
| B | LEU406 |
| B | MET407 |
| B | ARG408 |
| B | PHE409 |
| B | ASN418 |
| B | LYS420 |
| B | ASP459 |
| B | ASN460 |
| B | HIS461 |
| B | TYR465 |
| B | TYR514 |
| B | HOH729 |
| B | HOH735 |
Functional Information from PROSITE/UniProt
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLknqGAtCYMNSlLQ |
| Chain | Residue | Details |
| A | GLY215-GLN230 | |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YiLhAVlvHsGdnhg..GHY |
| Chain | Residue | Details |
| A | TYR448-TYR465 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS223 | |
| B | CYS223 | |
| Chain | Residue | Details |
| A | HIS464 | |
| B | HIS464 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| A | ASN218 | electrostatic stabiliser |
| A | CYS223 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS464 | proton acceptor, proton donor |
| A | ASP481 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| B | ASN218 | electrostatic stabiliser |
| B | CYS223 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS464 | proton acceptor, proton donor |
| B | ASP481 | electrostatic stabiliser |
