Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6LXB

X-ray structure of human PPARalpha ligand binding domain-saroglitazar co-crystals obtained by soaking

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue EWR A 501
ChainResidue
AILE272
AMET330
AVAL332
AALA333
ATYR334
AMET355
AHIS440
ATYR464
APHE273
ACYS275
ACYS276
ACYS278
ATHR279
ASER280
ATYR314
ALEU321

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:19116277, ECO:0007744|PDB:3ET1
ChainResidueDetails
ASER280
ATYR314
ATYR464

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Essential for heterodimerization with RXRA
ChainResidueDetails
ALEU433

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon