6LUE
Crystal structure of mouse Cryptochrome 1 in complex with compound KL201
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue EUL A 501 |
| Chain | Residue |
| A | TRP292 |
| A | TRP399 |
| A | LEU400 |
| A | HOH713 |
| A | HOH743 |
| B | ASP203 |
| A | HIS355 |
| A | ARG358 |
| A | PHE381 |
| A | ALA388 |
| A | ILE392 |
| A | ASN393 |
| A | SER396 |
| A | TRP397 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue EUL B 501 |
| Chain | Residue |
| A | ASP203 |
| B | TRP292 |
| B | HIS355 |
| B | ARG358 |
| B | PHE381 |
| B | ALA388 |
| B | ILE392 |
| B | ASN393 |
| B | SER396 |
| B | TRP397 |
| B | LEU400 |
| B | HOH655 |
| B | HOH711 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23746849 |
| Chain | Residue | Details |
| A | HIS355 | |
| A | ASP387 | |
| B | SER252 | |
| B | GLN289 | |
| B | HIS355 | |
| B | ASP387 | |
| A | SER252 | |
| A | GLN289 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by AMPK => ECO:0000269|PubMed:19833968 |
| Chain | Residue | Details |
| B | SER71 | |
| B | SER280 | |
| A | SER280 | |
| A | SER71 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MAPK => ECO:0000269|PubMed:15298678 |
| Chain | Residue | Details |
| A | SER247 | |
| B | SER247 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:23452855 |
| Chain | Residue | Details |
| A | LYS11 | |
| B | LYS11 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23452856 |
| Chain | Residue | Details |
| A | LYS159 | |
| A | LYS329 | |
| A | LYS485 | |
| B | LYS107 | |
| B | LYS159 | |
| B | LYS329 | |
| B | LYS485 | |
| A | LYS107 |
