Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004478 | molecular_function | methionine adenosyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006556 | biological_process | S-adenosylmethionine biosynthetic process |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004478 | molecular_function | methionine adenosyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006556 | biological_process | S-adenosylmethionine biosynthetic process |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue 3PO A 501 |
| Chain | Residue |
| A | HIS34 |
| A | HOH635 |
| A | HOH645 |
| A | HOH665 |
| A | HOH723 |
| A | HOH731 |
| A | HOH732 |
| A | HOH765 |
| B | ASP139 |
| B | GLY288 |
| B | ALA289 |
| A | ASP36 |
| B | LYS293 |
| B | ASP299 |
| B | HOH629 |
| A | LYS189 |
| A | ASP266 |
| A | ARG272 |
| A | LYS273 |
| A | MG502 |
| A | EU9503 |
| A | HOH620 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | ASP36 |
| A | 3PO501 |
| A | HOH635 |
| A | HOH645 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue EU9 A 503 |
| Chain | Residue |
| A | HIS34 |
| A | PRO35 |
| A | ASP187 |
| A | LYS189 |
| A | SER255 |
| A | ARG257 |
| A | PHE258 |
| A | ASP266 |
| A | 3PO501 |
| A | HOH620 |
| A | HOH624 |
| A | HOH666 |
| A | HOH677 |
| A | HOH716 |
| B | ALA60 |
| B | GLU75 |
| B | GLN118 |
| B | SER119 |
| B | GLN121 |
| B | GLY138 |
| B | ASP139 |
| B | LYS297 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | binding site for residue 3PO B 501 |
| Chain | Residue |
| A | ASP139 |
| A | GLY288 |
| A | ALA289 |
| A | LYS293 |
| A | ASP299 |
| A | HOH622 |
| A | HOH708 |
| A | HOH725 |
| B | HIS34 |
| B | ASP36 |
| B | LYS189 |
| B | ARG272 |
| B | LYS273 |
| B | MG502 |
| B | EU9503 |
| B | HOH616 |
| B | HOH627 |
| B | HOH655 |
| B | HOH660 |
| B | HOH725 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | ASP36 |
| B | LYS273 |
| B | 3PO501 |
| B | HOH627 |
| B | HOH660 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | binding site for residue EU9 B 503 |
| Chain | Residue |
| A | ALA60 |
| A | GLU75 |
| A | GLN118 |
| A | SER119 |
| A | GLN121 |
| A | GLY138 |
| A | ASP139 |
| A | LYS297 |
| B | HIS34 |
| B | PRO35 |
| B | ASP187 |
| B | LYS189 |
| B | SER214 |
| B | SER255 |
| B | ARG257 |
| B | PHE258 |
| B | ASP266 |
| B | 3PO501 |
| B | HOH612 |
| B | HOH616 |
| B | HOH620 |
| B | HOH664 |
| B | HOH716 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 10 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGrFTIGGP |
| Chain | Residue | Details |
| A | PRO254-PRO263 | |
| site_id | PS00376 |
| Number of Residues | 11 |
| Details | ADOMET_SYNTHASE_1 S-adenosylmethionine synthase signature 1. GAGDQGmmfGY |
| Chain | Residue | Details |
| A | GLY136-TYR146 | |
| site_id | PS00377 |
| Number of Residues | 9 |
| Details | ADOMET_SYNTHASE_2 S-adenosylmethionine synthase signature 2. GGGAFSgKD |
| Chain | Residue | Details |
| A | GLY286-ASP294 | |
