6LR3

Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004167	molecular_function	dopachrome isomerase activity
A	0005576	cellular_component	extracellular region
A	0050178	molecular_function	phenylpyruvate tautomerase activity
B	0004167	molecular_function	dopachrome isomerase activity
B	0005576	cellular_component	extracellular region
B	0050178	molecular_function	phenylpyruvate tautomerase activity
C	0004167	molecular_function	dopachrome isomerase activity
C	0005576	cellular_component	extracellular region
C	0050178	molecular_function	phenylpyruvate tautomerase activity
D	0004167	molecular_function	dopachrome isomerase activity
D	0005576	cellular_component	extracellular region
D	0050178	molecular_function	phenylpyruvate tautomerase activity
E	0004167	molecular_function	dopachrome isomerase activity
E	0005576	cellular_component	extracellular region
E	0050178	molecular_function	phenylpyruvate tautomerase activity
F	0004167	molecular_function	dopachrome isomerase activity
F	0005576	cellular_component	extracellular region
F	0050178	molecular_function	phenylpyruvate tautomerase activity
G	0004167	molecular_function	dopachrome isomerase activity
G	0005576	cellular_component	extracellular region
G	0050178	molecular_function	phenylpyruvate tautomerase activity
H	0004167	molecular_function	dopachrome isomerase activity
H	0005576	cellular_component	extracellular region
H	0050178	molecular_function	phenylpyruvate tautomerase activity
I	0004167	molecular_function	dopachrome isomerase activity
I	0005576	cellular_component	extracellular region
I	0050178	molecular_function	phenylpyruvate tautomerase activity
J	0004167	molecular_function	dopachrome isomerase activity
J	0005576	cellular_component	extracellular region
J	0050178	molecular_function	phenylpyruvate tautomerase activity
K	0004167	molecular_function	dopachrome isomerase activity
K	0005576	cellular_component	extracellular region
K	0050178	molecular_function	phenylpyruvate tautomerase activity
L	0004167	molecular_function	dopachrome isomerase activity
L	0005576	cellular_component	extracellular region
L	0050178	molecular_function	phenylpyruvate tautomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG98
A	ILE100
A	HOH301
C	ARG98
C	ILE100
D	ARG98
D	ILE100

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 D 201

Chain	Residue
C	HOH259
D	ARG43
D	HOH371
D	HOH379
A	ARG43
C	ARG43

---

site_id	AC3
Number of Residues	8
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG98
B	ILE100
B	HOH302
B	HOH388
E	ARG98
E	ILE100
F	ARG98
F	ILE100

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 F 201

Chain	Residue
B	ARG43
E	ARG43
F	ARG43
F	HOH329
F	HOH361
F	HOH369

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 G 201

Chain	Residue
G	ARG43
G	HOH353
G	HOH363
G	HOH383
H	ARG43
I	ARG43

---

site_id	AC6
Number of Residues	7
Details	binding site for residue SO4 G 202

Chain	Residue
G	ARG98
G	ILE100
G	HOH406
H	ARG98
H	ILE100
I	ARG98
I	ILE100

---

site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 J 201

Chain	Residue
J	ARG43
J	HOH361
J	HOH371
K	ARG43
L	ARG43
L	HOH285

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SO4 J 202

Chain	Residue
J	ARG98
J	ILE100
J	HOH312
J	HOH396
K	ARG98
K	ILE100
L	ARG98
L	ILE100

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