6LQX
Crystal structure of the CBP bromodomain in complex with small molecule LC-CPin7
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004402 | molecular_function | histone acetyltransferase activity |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0004402 | molecular_function | histone acetyltransferase activity |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
C | 0004402 | molecular_function | histone acetyltransferase activity |
C | 0006355 | biological_process | regulation of DNA-templated transcription |
D | 0004402 | molecular_function | histone acetyltransferase activity |
D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue EOO B 1201 |
Chain | Residue |
B | LEU1109 |
B | PRO1110 |
B | LEU1120 |
B | ILE1122 |
B | ASN1168 |
B | ARG1173 |
B | VAL1174 |
B | HOH1309 |
site_id | AC2 |
Number of Residues | 2 |
Details | binding site for residue NA B 1202 |
Chain | Residue |
C | NA1202 |
C | TRP1165 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue NA B 1203 |
Chain | Residue |
B | ALA1182 |
C | NA1201 |
site_id | AC4 |
Number of Residues | 2 |
Details | binding site for residue NA C 1201 |
Chain | Residue |
B | NA1203 |
C | TRP1165 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue NA C 1202 |
Chain | Residue |
B | TYR1175 |
B | NA1202 |
C | GLU1186 |
Functional Information from PROSITE/UniProt
site_id | PS00633 |
Number of Residues | 60 |
Details | BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY |
Chain | Residue | Details |
B | SER1108-TYR1167 |