Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6LOI

Crystal structure of Enterococcus faecalis Undecaprenyl pyrophosphate synthase(EfaUPPS)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0002094	molecular_function	polyprenyltransferase activity
A	0004659	molecular_function	prenyltransferase activity
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0030145	molecular_function	manganese ion binding
A	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0002094	molecular_function	polyprenyltransferase activity
B	0004659	molecular_function	prenyltransferase activity
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0030145	molecular_function	manganese ion binding
B	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0002094	molecular_function	polyprenyltransferase activity
C	0004659	molecular_function	prenyltransferase activity
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
C	0016094	biological_process	polyprenol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0030145	molecular_function	manganese ion binding
C	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0002094	molecular_function	polyprenyltransferase activity
D	0004659	molecular_function	prenyltransferase activity
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
D	0016094	biological_process	polyprenol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0030145	molecular_function	manganese ion binding
D	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0002094	molecular_function	polyprenyltransferase activity
E	0004659	molecular_function	prenyltransferase activity
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
E	0016094	biological_process	polyprenol biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
E	0030145	molecular_function	manganese ion binding
E	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0002094	molecular_function	polyprenyltransferase activity
F	0004659	molecular_function	prenyltransferase activity
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0008834	molecular_function	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
F	0016094	biological_process	polyprenol biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
F	0030145	molecular_function	manganese ion binding
F	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
F	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01066
Number of Residues	18
Details	UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. ELLIRTSGeeRiSnFLLW

Chain	Residue	Details
A	GLU197-TRP214

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_01139

Chain	Residue	Details
A	ASP29
B	ASP29
C	ASP29
D	ASP29
E	ASP29
F	ASP29

site_id	SWS_FT_FI2
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000255\|HAMAP-Rule:MF_01139

Chain	Residue	Details
A	ASN77
B	ASN77
C	ASN77
D	ASN77
E	ASN77
F	ASN77

site_id	SWS_FT_FI3
Number of Residues	66
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01139

Chain	Residue	Details
B	GLY30
B	TRP34
B	ARG42
B	HIS46
B	SER74
B	TRP78
B	ARG80
B	ARG201
B	ARG207
B	GLU220
C	ASP29
C	GLY30
C	TRP34
C	ARG42
C	HIS46
C	SER74
C	TRP78
C	ARG80
C	ARG201
C	ARG207
C	GLU220
D	ASP29
D	GLY30
D	TRP34
D	ARG42
D	HIS46
D	SER74
D	TRP78
D	ARG80
D	ARG201
D	ARG207
D	GLU220
E	ASP29
E	GLY30
E	TRP34
E	ARG42
E	HIS46
E	SER74
E	TRP78
E	ARG80
E	ARG201
E	ARG207
E	GLU220
F	ASP29
F	GLY30
F	TRP34
F	ARG42
F	HIS46
F	SER74
F	TRP78
F	ARG80
F	ARG201
F	ARG207
F	GLU220
A	ARG42
A	HIS46
A	SER74
A	TRP78
A	ARG80
A	ARG201
A	ARG207
A	GLU220
B	ASP29
A	ASP29
A	GLY30
A	TRP34

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)