6LFK

Crystal structure of KatE from atypical E. coli

Replaces:  6JOA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0004601	molecular_function	peroxidase activity
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0020037	molecular_function	heme binding
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004096	molecular_function	catalase activity
B	0004601	molecular_function	peroxidase activity
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0020037	molecular_function	heme binding
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004096	molecular_function	catalase activity
C	0004601	molecular_function	peroxidase activity
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0020037	molecular_function	heme binding
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004096	molecular_function	catalase activity
D	0004601	molecular_function	peroxidase activity
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0020037	molecular_function	heme binding
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue HEM A 801

Chain	Residue
A	ARG125
A	ASN201
A	PHE206
A	PHE214
A	HIS275
A	PHE391
A	LEU407
A	ARG411
A	SER414
A	TYR415
A	THR418
A	VAL126
A	GLN419
A	ARG422
A	HOH912
A	HOH927
C	ASP118
A	VAL127
A	HIS128
A	ARG165
A	GLY184
A	TRP185
A	VAL199
A	GLY200

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site_id	AC2
Number of Residues	25
Details	binding site for residue HEM C 801

Chain	Residue
A	ASP118
C	ARG125
C	VAL127
C	HIS128
C	ARG165
C	GLY184
C	TRP185
C	VAL199
C	GLY200
C	ASN201
C	PHE206
C	PHE214
C	ILE274
C	HIS275
C	PHE391
C	LEU407
C	ARG411
C	SER414
C	TYR415
C	THR418
C	GLN419
C	ARG422
C	HOH936
C	HOH948
C	HOH993

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Functional Information from PROSITE/UniProt

site_id	PS00437
Number of Residues	9
Details	CATALASE_1 Catalase proximal heme-ligand signature. RLFSYiDTQ

Chain	Residue	Details
A	ARG411-GLN419

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site_id	PS00438
Number of Residues	17
Details	CATALASE_2 Catalase proximal active site signature. FdHeripERvvHarGTG

Chain	Residue	Details
A	PHE117-GLY133

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