6LD3

Zika NS5 polymerase domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0005524	molecular_function	ATP binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 901

Chain	Residue
A	GLU439
A	HIS443
A	CYS448
A	CYS451

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 902

Chain	Residue
A	HIS714
A	CYS730
A	CYS849
A	HOH1053

---

site_id	AC3
Number of Residues	14
Details	binding site for residues KY3 A 903 and FB2 A 904

Chain	Residue
A	CYS711
A	HIS713
A	ARG731
A	ARG739
A	MET763
A	LEU767
A	THR795
A	THR796
A	TRP797
A	SER798
A	HIS800
A	GLY801
A	HOH1129
A	LEU513

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"Nuclear localization signal (NLS)","evidences":[{"source":"UniProtKB","id":"Q32ZE1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q32ZE1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P14335","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---