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6LB8

Crystal structure of the Ca2+-free T4L-MICU1-MICU2 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003796molecular_functionlysozyme activity
A0005509molecular_functioncalcium ion binding
A0006851biological_processmitochondrial calcium ion transmembrane transport
A0009253biological_processpeptidoglycan catabolic process
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0016998biological_processcell wall macromolecule catabolic process
A0030430cellular_componenthost cell cytoplasm
A0031640biological_processkilling of cells of another organism
A0042742biological_processdefense response to bacterium
A0044659biological_processviral release from host cell by cytolysis
B0005509molecular_functioncalcium ion binding
B0006851biological_processmitochondrial calcium ion transmembrane transport
C0003796molecular_functionlysozyme activity
C0005509molecular_functioncalcium ion binding
C0006851biological_processmitochondrial calcium ion transmembrane transport
C0009253biological_processpeptidoglycan catabolic process
C0016798molecular_functionhydrolase activity, acting on glycosyl bonds
C0016998biological_processcell wall macromolecule catabolic process
C0030430cellular_componenthost cell cytoplasm
C0031640biological_processkilling of cells of another organism
C0042742biological_processdefense response to bacterium
C0044659biological_processviral release from host cell by cytolysis
D0005509molecular_functioncalcium ion binding
D0006851biological_processmitochondrial calcium ion transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DLNGDGEVDmeEF
ChainResidueDetails
AASP231-PHE243
AASP421-PHE433

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBINDING: BINDING => ECO:0000269|PubMed:31397067, ECO:0000269|PubMed:32790952, ECO:0007744|PDB:6IIH, ECO:0007744|PDB:6LB7
ChainResidueDetails
BASP185
DGLU196
BASP187
BASN189
BMET191
BGLU196
DASP185
DASP187
DASN189
DMET191

site_idSWS_FT_FI2
Number of Residues12
DetailsBINDING: BINDING => ECO:0000269|PubMed:31397067, ECO:0007744|PDB:6IIH
ChainResidueDetails
BGLU193
DASP379
DCYS381
DGLU386
BASP375
BASP377
BASP379
BCYS381
BGLU386
DGLU193
DASP375
DASP377

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
BSER205
DSER205

226707

PDB entries from 2024-10-30

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