6L9W

Crystal structure of mouse TIFA (T9E/C36S mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000151	cellular_component	ubiquitin ligase complex
A	0002376	biological_process	immune system process
A	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
A	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
A	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
A	0045087	biological_process	innate immune response
A	0051260	biological_process	protein homooligomerization
B	0000151	cellular_component	ubiquitin ligase complex
B	0002376	biological_process	immune system process
B	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
B	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
B	0045087	biological_process	innate immune response
B	0051260	biological_process	protein homooligomerization
C	0000151	cellular_component	ubiquitin ligase complex
C	0002376	biological_process	immune system process
C	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
C	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
C	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
C	0045087	biological_process	innate immune response
C	0051260	biological_process	protein homooligomerization
D	0000151	cellular_component	ubiquitin ligase complex
D	0002376	biological_process	immune system process
D	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
D	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
D	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
D	0045087	biological_process	innate immune response
D	0051260	biological_process	protein homooligomerization
E	0000151	cellular_component	ubiquitin ligase complex
E	0002376	biological_process	immune system process
E	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
E	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
E	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
E	0045087	biological_process	innate immune response
E	0051260	biological_process	protein homooligomerization
F	0000151	cellular_component	ubiquitin ligase complex
F	0002376	biological_process	immune system process
F	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
F	0043122	biological_process	regulation of canonical NF-kappaB signal transduction
F	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
F	0045087	biological_process	innate immune response
F	0051260	biological_process	protein homooligomerization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	336
Details	Domain: {"description":"FHA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00086","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q96CG3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---