6L9C

Neutron structure of copper amine oxidase from Arthrobacter glibiformis at pD 7.4

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005507	molecular_function	copper ion binding
X	0008131	molecular_function	primary methylamine oxidase activity
X	0009308	biological_process	amine metabolic process
X	0016491	molecular_function	oxidoreductase activity
X	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CU X 701

Chain	Residue
X	HIS431
X	HIS433
X	HIS592
X	HOH1031
X	HOH1415

---

site_id	AC2
Number of Residues	5
Details	binding site for residue NA X 702

Chain	Residue
X	HOH1185
X	ASP440
X	MET441
X	ASP581
X	ILE582

---

site_id	AC3
Number of Residues	15
Details	binding site for Ligand residues TPQ X 382 through ASP X 383 bound to ASN X 381

Chain	Residue
X	VAL282
X	TYR284
X	TYR296
X	ASA298
X	THR377
X	THR378
X	ILE379
X	GLY380
X	ASN381
X	TYR384
X	THR403
X	GLY404
X	HIS433
X	HOH1239
X	HOH1415

---

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY

Chain	Residue	Details
X	MET371-TYR384

---

site_id	PS01165
Number of Residues	14
Details	COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP

Chain	Residue	Details
X	THR587-PRO600

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Schiff-base intermediate with substrate; via topaquinone","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AV4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W4N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BT3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZL8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KN4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"2',4',5'-topaquinone","evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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