6L8U

Crystal structure of human BCDIN3D in complex with SAH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001510	biological_process	RNA methylation
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008168	molecular_function	methyltransferase activity
A	0008171	molecular_function	O-methyltransferase activity
A	0008173	molecular_function	RNA methyltransferase activity
A	0008175	molecular_function	tRNA methyltransferase activity
A	0010586	biological_process	miRNA metabolic process
A	0016740	molecular_function	transferase activity
A	0030488	biological_process	tRNA methylation
A	0031054	biological_process	pre-miRNA processing
A	0032259	biological_process	methylation
A	0070883	molecular_function	pre-miRNA binding
A	0090486	molecular_function	small RNA 2'-O-methyltransferase activity
A	2000632	biological_process	negative regulation of pre-miRNA processing
B	0001510	biological_process	RNA methylation
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008168	molecular_function	methyltransferase activity
B	0008171	molecular_function	O-methyltransferase activity
B	0008173	molecular_function	RNA methyltransferase activity
B	0008175	molecular_function	tRNA methyltransferase activity
B	0010586	biological_process	miRNA metabolic process
B	0016740	molecular_function	transferase activity
B	0030488	biological_process	tRNA methylation
B	0031054	biological_process	pre-miRNA processing
B	0032259	biological_process	methylation
B	0070883	molecular_function	pre-miRNA binding
B	0090486	molecular_function	small RNA 2'-O-methyltransferase activity
B	2000632	biological_process	negative regulation of pre-miRNA processing
C	0001510	biological_process	RNA methylation
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008168	molecular_function	methyltransferase activity
C	0008171	molecular_function	O-methyltransferase activity
C	0008173	molecular_function	RNA methyltransferase activity
C	0008175	molecular_function	tRNA methyltransferase activity
C	0010586	biological_process	miRNA metabolic process
C	0016740	molecular_function	transferase activity
C	0030488	biological_process	tRNA methylation
C	0031054	biological_process	pre-miRNA processing
C	0032259	biological_process	methylation
C	0070883	molecular_function	pre-miRNA binding
C	0090486	molecular_function	small RNA 2'-O-methyltransferase activity
C	2000632	biological_process	negative regulation of pre-miRNA processing
D	0001510	biological_process	RNA methylation
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008168	molecular_function	methyltransferase activity
D	0008171	molecular_function	O-methyltransferase activity
D	0008173	molecular_function	RNA methyltransferase activity
D	0008175	molecular_function	tRNA methyltransferase activity
D	0010586	biological_process	miRNA metabolic process
D	0016740	molecular_function	transferase activity
D	0030488	biological_process	tRNA methylation
D	0031054	biological_process	pre-miRNA processing
D	0032259	biological_process	methylation
D	0070883	molecular_function	pre-miRNA binding
D	0090486	molecular_function	small RNA 2'-O-methyltransferase activity
D	2000632	biological_process	negative regulation of pre-miRNA processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue SAH A 1001

Chain	Residue
A	PHE31
A	LEU134
A	ASP135
A	PHE136
A	MET164
A	SER165
A	ILE166
A	ILE170
A	HOH2001
A	GLY32
A	ASN33
A	ARG46
A	GLY74
A	ASN76
A	LEU80
A	ASP110
A	ILE111

---

site_id	AC2
Number of Residues	18
Details	binding site for residue SAH B 1001

Chain	Residue
B	PHE31
B	GLY32
B	ASN33
B	TYR37
B	ARG46
B	GLY74
B	ASN76
B	ASP110
B	ILE111
B	LEU134
B	ASP135
B	PHE136
B	MET137
B	MET164
B	SER165
B	ILE166
B	TRP169
B	HOH2001

---

site_id	AC3
Number of Residues	16
Details	binding site for residue SAH C 1001

Chain	Residue
C	PHE31
C	GLY32
C	TYR37
C	SER38
C	ARG46
C	GLY74
C	ASN76
C	LEU80
C	ASP110
C	ILE111
C	LEU134
C	ASP135
C	PHE136
C	MET164
C	SER165
C	ILE166

---

site_id	AC4
Number of Residues	18
Details	binding site for residue SAH D 1001

Chain	Residue
D	PHE31
D	GLY32
D	ASN33
D	ARG46
D	GLY74
D	ASN76
D	LEU80
D	ASP110
D	ILE111
D	LEU134
D	ASP135
D	PHE136
D	MET164
D	SER165
D	ILE166
D	TRP169
D	ILE170
D	HOH2001

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31919512","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6L8U","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

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