6L6S

The structure of the UdgX mutant H109E crosslinked to single-stranded DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004844	molecular_function	uracil DNA N-glycosylase activity
A	0006281	biological_process	DNA repair
A	0016779	molecular_function	nucleotidyltransferase activity
A	0046872	molecular_function	metal ion binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0004844	molecular_function	uracil DNA N-glycosylase activity
B	0006281	biological_process	DNA repair
B	0016779	molecular_function	nucleotidyltransferase activity
B	0046872	molecular_function	metal ion binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SF4 A 301

Chain	Residue
A	CYS24
A	GLY26
A	CYS27
A	HIS95
A	CYS120
A	TRP123

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site_id	AC2
Number of Residues	7
Details	binding site for residue SF4 B 301

Chain	Residue
B	TYR30
B	HIS95
B	CYS120
B	TRP123
B	CYS24
B	GLY26
B	CYS27

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site_id	AC3
Number of Residues	36
Details	binding site for Poly-Saccharide residues DG C 7 through GLU A 109

Chain	Residue
A	ALA4
A	GLN5
A	ASP6
A	HIS10
A	THR11
A	GLU23
A	ARG25
A	GLU52
A	GLN53
A	PRO68
A	ALA69
A	PHE96
A	LYS97
A	ILE108
A	LYS110
A	TRP123
A	ALA126
A	HIS178
A	SER180
A	SER181
A	LEU183
A	ARG184
A	HOH408
A	HOH413
A	HOH415
A	HOH418
A	HOH464
A	HOH467
C	DT6
C	DG10
C	HOH104
C	HOH106
C	HOH108
C	HOH119
C	HOH122
C	HOH123

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site_id	AC4
Number of Residues	29
Details	binding site for Di-Saccharide ORP C 8 and DA C 9

Chain	Residue
A	ALA4
A	GLN5
A	ASP6
A	PHE7
A	HIS10
A	THR11
A	GLU52
A	GLN53
A	PRO68
A	ALA69
A	PHE96
A	LYS97
A	ILE108
A	LYS110
A	ALA126
A	HIS178
A	SER180
A	SER181
A	ARG184
A	HOH408
A	HOH413
A	HOH415
A	HOH418
A	HOH467
C	DG7
C	DG10
C	HOH104
C	HOH122
C	HOH123

---

site_id	AC5
Number of Residues	24
Details	binding site for Poly-Saccharide residues DG D 7 through GLU B 109

Chain	Residue
D	HOH110
D	HOH113
D	HOH114
B	GLU52
B	GLN53
B	PRO54
B	GLY55
B	GLY67
B	PRO68
B	ALA69
B	PHE96
B	LYS97
B	ILE108
B	LYS110
B	HIS178
B	SER180
B	SER181
B	LEU183
B	ARG184
B	HOH417
D	DT6
D	DG10
D	HOH102
D	HOH104

---

site_id	AC6
Number of Residues	16
Details	binding site for Di-Saccharide ORP D 8 and DA D 9

Chain	Residue
B	GLY67
B	PRO68
B	ALA69
B	GLU109
B	HIS178
B	SER180
B	SER181
B	ARG184
B	HOH417
D	DG7
D	DG10
D	HOH102
D	HOH109
D	HOH110
D	HOH113
D	HOH114

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