6L6P

hASIC2a co-crystallized with Mamb-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005272	molecular_function	sodium channel activity
A	0006814	biological_process	sodium ion transport
A	0015280	molecular_function	ligand-gated sodium channel activity
A	0016020	cellular_component	membrane
B	0005272	molecular_function	sodium channel activity
B	0006814	biological_process	sodium ion transport
B	0015280	molecular_function	ligand-gated sodium channel activity
B	0016020	cellular_component	membrane
C	0005272	molecular_function	sodium channel activity
C	0006814	biological_process	sodium ion transport
C	0015280	molecular_function	ligand-gated sodium channel activity
C	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS01206
Number of Residues	21
Details	ASC Amiloride-sensitive sodium channels signature. YsiTaCridCeTryIVenCnC

Chain	Residue	Details
A	TYR302-CYS322

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	105
Details	TRANSMEM: Helical => ECO:0000305|Ref.10, ECO:0007744|PDB:6L6P

Chain	Residue	Details
A	VAL43-VAL64
A	VAL425-PHE439
B	VAL43-VAL64
B	VAL425-PHE439
C	VAL43-VAL64
C	VAL425-PHE439

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site_id	SWS_FT_FI2
Number of Residues	1077
Details	TOPO_DOM: Extracellular => ECO:0000305|Ref.10

Chain	Residue	Details
A	SER65-GLU424
B	SER65-GLU424
C	SER65-GLU424

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site_id	SWS_FT_FI3
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN365
A	ASN392
B	ASN365
B	ASN392
C	ASN365
C	ASN392

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