6L6P
hASIC2a co-crystallized with Mamb-1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005272 | molecular_function | sodium channel activity |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0015280 | molecular_function | ligand-gated sodium channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0005272 | molecular_function | sodium channel activity |
| B | 0006814 | biological_process | sodium ion transport |
| B | 0015280 | molecular_function | ligand-gated sodium channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0005272 | molecular_function | sodium channel activity |
| C | 0006814 | biological_process | sodium ion transport |
| C | 0015280 | molecular_function | ligand-gated sodium channel activity |
| C | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS01206 |
| Number of Residues | 21 |
| Details | ASC Amiloride-sensitive sodium channels signature. YsiTaCridCeTryIVenCnC |
| Chain | Residue | Details |
| A | TYR302-CYS322 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 105 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"OCT-2019","submissionDatabase":"PDB data bank","title":"hASIC2a co-crystallized with Mamb-1.","authors":["Lei F.","Jian S."]}},{"source":"PDB","id":"6L6P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Motif: {"description":"GAS motif; ion selectivity filter","evidences":[{"source":"UniProtKB","id":"P78348","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
