6L5N
Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue ANP A 601 |
| Chain | Residue |
| A | GLY205 |
| A | LYS236 |
| A | THR237 |
| A | GLU340 |
| A | GLY500 |
| A | ASP502 |
| A | ARG527 |
| A | ARG530 |
| A | ALA531 |
| A | MG602 |
| A | HOH716 |
| A | VAL206 |
| A | HOH718 |
| A | HOH723 |
| A | HOH730 |
| A | HOH741 |
| A | HOH743 |
| A | HOH747 |
| A | HOH753 |
| A | HOH759 |
| A | HOH760 |
| A | HOH773 |
| A | PHE208 |
| A | PHE210 |
| A | GLN213 |
| A | THR232 |
| A | GLY233 |
| A | THR234 |
| A | GLY235 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | GLU340 |
| A | ANP601 |
| A | HOH716 |
| A | HOH718 |
| A | HOH723 |
| A | HOH743 |
| site_id | AC3 |
| Number of Residues | 31 |
| Details | binding site for residue ANP B 601 |
| Chain | Residue |
| B | ARG204 |
| B | GLY205 |
| B | VAL206 |
| B | PHE208 |
| B | PHE210 |
| B | GLN213 |
| B | THR232 |
| B | GLY233 |
| B | THR234 |
| B | GLY235 |
| B | LYS236 |
| B | THR237 |
| B | PHE238 |
| B | GLU340 |
| B | GLY500 |
| B | ASP502 |
| B | ARG527 |
| B | ARG530 |
| B | ALA531 |
| B | MG603 |
| B | HOH713 |
| B | HOH716 |
| B | HOH717 |
| B | HOH724 |
| B | HOH726 |
| B | HOH731 |
| B | HOH735 |
| B | HOH739 |
| B | HOH744 |
| B | HOH750 |
| B | HOH751 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue ANP B 602 |
| Chain | Residue |
| A | LYS474 |
| A | GLN475 |
| A | ILE478 |
| B | ASP346 |
| B | MSE347 |
| B | HIS380 |
| B | TRP381 |
| B | LYS555 |
| B | MG604 |
| B | HOH704 |
| B | HOH738 |
| B | HOH742 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 603 |
| Chain | Residue |
| B | ASP339 |
| B | ANP601 |
| B | HOH713 |
| B | HOH717 |
| B | HOH726 |
| B | HOH739 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 604 |
| Chain | Residue |
| B | ANP602 |
| B | HOH704 |
| B | HOH742 |
| B | HOH753 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAD box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
