Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004935 | molecular_function | adrenergic receptor activity |
| A | 0004938 | molecular_function | alpha2-adrenergic receptor activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006940 | biological_process | regulation of smooth muscle contraction |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0016020 | cellular_component | membrane |
| A | 0019229 | biological_process | regulation of vasoconstriction |
| A | 0020037 | molecular_function | heme binding |
| A | 0022900 | biological_process | electron transport chain |
| A | 0030168 | biological_process | platelet activation |
| A | 0042597 | cellular_component | periplasmic space |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 1201 |
| Chain | Residue |
| A | HIS1063 |
| A | ASP1066 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue E39 A 1202 |
| Chain | Residue |
| A | PHE412 |
| A | TYR416 |
| A | ASP113 |
| A | VAL114 |
| A | CYS117 |
| A | SER204 |
| A | TRP387 |
| A | PHE390 |
| A | PHE391 |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSAwHLCAISLDRYWsI |
| Chain | Residue | Details |
| A | SER119-ILE135 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU34-PHE59 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 31 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250 |
| Chain | Residue | Details |
| A | THR60-LEU70 | |
| A | ASP130-LYS151 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE71-MET96 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 43 |
| Details | TOPO_DOM: Extracellular => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY97-CYS106 | |
| A | GLU173-LYS194 | |
| A | LEU396-LYS409 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU107-LEU129 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA152-ILE172 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000250 |
| Chain | Residue | Details |
| A | TRP195-VAL217 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000250 |
| Chain | Residue | Details |
| A | VAL375-THR395 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE410-PHE429 | |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | SITE: Implicated in ligand binding |
| Chain | Residue | Details |
| A | ASP113 | |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | SITE: Implicated in catechol agonist binding and receptor activation |
| Chain | Residue | Details |
| A | SER200 | |
| A | SER204 | |
| Chain | Residue | Details |
| A | LYS1077 | |
| Chain | Residue | Details |
| A | ASN1099 | |
| site_id | SWS_FT_FI14 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS442 | |
