Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004743 | molecular_function | pyruvate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051289 | biological_process | protein homotetramerization |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004743 | molecular_function | pyruvate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0030955 | molecular_function | potassium ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051289 | biological_process | protein homotetramerization |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004743 | molecular_function | pyruvate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| C | 0030955 | molecular_function | potassium ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051289 | biological_process | protein homotetramerization |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004743 | molecular_function | pyruvate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006096 | biological_process | glycolytic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
| D | 0030955 | molecular_function | potassium ion binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051289 | biological_process | protein homotetramerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | GLU257 |
| A | ASP281 |
| A | ATP603 |
| A | OXL605 |
| A | HOH773 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | ATP603 |
| A | HOH714 |
| A | HOH745 |
| A | HOH794 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | binding site for residue ATP A 603 |
| Chain | Residue |
| A | THR44 |
| A | LEU45 |
| A | PRO47 |
| A | ARG67 |
| A | ASN69 |
| A | HIS72 |
| A | HIS78 |
| A | ARG109 |
| A | LYS191 |
| A | ASN192 |
| A | LYS255 |
| A | ASP281 |
| A | SER347 |
| A | GLY348 |
| A | ALA351 |
| A | MG601 |
| A | MG602 |
| A | K604 |
| A | OXL605 |
| A | HOH708 |
| A | HOH710 |
| A | HOH714 |
| A | HOH721 |
| A | HOH745 |
| A | HOH763 |
| A | HOH794 |
| A | HOH832 |
| A | HOH839 |
| A | HOH852 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue K A 604 |
| Chain | Residue |
| A | ASN69 |
| A | SER71 |
| A | ASP102 |
| A | THR103 |
| A | SER228 |
| A | ATP603 |
| A | HOH704 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue OXL A 605 |
| Chain | Residue |
| A | LYS255 |
| A | GLU257 |
| A | ALA278 |
| A | ARG279 |
| A | GLY280 |
| A | ASP281 |
| A | THR313 |
| A | MG601 |
| A | ATP603 |
| A | HOH714 |
| A | HOH794 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | GLU257 |
| B | ASP281 |
| B | ATP603 |
| B | OXL605 |
| B | HOH754 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | SER347 |
| B | ATP603 |
| B | HOH705 |
| B | HOH708 |
| B | HOH743 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | binding site for residue ATP B 603 |
| Chain | Residue |
| B | THR44 |
| B | LEU45 |
| B | PRO47 |
| B | ARG67 |
| B | ASN69 |
| B | HIS72 |
| B | HIS78 |
| B | ARG109 |
| B | LYS191 |
| B | ASN192 |
| B | LYS255 |
| B | ASP281 |
| B | SER347 |
| B | ALA351 |
| B | MG601 |
| B | MG602 |
| B | K604 |
| B | OXL605 |
| B | HOH705 |
| B | HOH715 |
| B | HOH730 |
| B | HOH735 |
| B | HOH743 |
| B | HOH806 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue K B 604 |
| Chain | Residue |
| B | ASN69 |
| B | SER71 |
| B | ASP102 |
| B | THR103 |
| B | SER228 |
| B | ATP603 |
| site_id | AD1 |
| Number of Residues | 12 |
| Details | binding site for residue OXL B 605 |
| Chain | Residue |
| B | ARG279 |
| B | GLY280 |
| B | ASP281 |
| B | THR313 |
| B | MG601 |
| B | ATP603 |
| B | HOH705 |
| B | HOH708 |
| B | HOH754 |
| B | LYS255 |
| B | GLU257 |
| B | ALA278 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 601 |
| Chain | Residue |
| C | GLU257 |
| C | ASP281 |
| C | ATP603 |
| C | OXL605 |
| C | HOH715 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 602 |
| Chain | Residue |
| C | ATP603 |
| C | HOH729 |
| C | HOH731 |
| C | HOH732 |
| site_id | AD4 |
| Number of Residues | 23 |
| Details | binding site for residue ATP C 603 |
| Chain | Residue |
| C | THR44 |
| C | LEU45 |
| C | PRO47 |
| C | ARG67 |
| C | ASN69 |
| C | HIS72 |
| C | ARG109 |
| C | LYS191 |
| C | ASN192 |
| C | LYS255 |
| C | ASP281 |
| C | SER347 |
| C | ALA351 |
| C | MG601 |
| C | MG602 |
| C | K604 |
| C | OXL605 |
| C | HOH702 |
| C | HOH722 |
| C | HOH731 |
| C | HOH732 |
| C | HOH769 |
| C | HOH812 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue K C 604 |
| Chain | Residue |
| C | ASN69 |
| C | SER71 |
| C | ASP102 |
| C | THR103 |
| C | SER228 |
| C | ATP603 |
| C | HOH707 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residue OXL C 605 |
| Chain | Residue |
| C | LYS255 |
| C | GLU257 |
| C | ALA278 |
| C | ARG279 |
| C | GLY280 |
| C | ASP281 |
| C | THR313 |
| C | MG601 |
| C | ATP603 |
| C | HOH715 |
| C | HOH732 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 601 |
| Chain | Residue |
| D | GLU257 |
| D | ASP281 |
| D | ATP603 |
| D | OXL605 |
| D | HOH712 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 602 |
| Chain | Residue |
| D | ATP603 |
| D | HOH706 |
| D | HOH742 |
| D | HOH809 |
| site_id | AD9 |
| Number of Residues | 28 |
| Details | binding site for residue ATP D 603 |
| Chain | Residue |
| D | THR44 |
| D | LEU45 |
| D | PRO47 |
| D | ARG67 |
| D | ASN69 |
| D | HIS72 |
| D | HIS78 |
| D | ASP102 |
| D | ARG109 |
| D | LYS191 |
| D | ASN192 |
| D | LYS255 |
| D | ASP281 |
| D | SER347 |
| D | GLY348 |
| D | ALA351 |
| D | MG601 |
| D | MG602 |
| D | K604 |
| D | OXL605 |
| D | HOH706 |
| D | HOH707 |
| D | HOH709 |
| D | HOH742 |
| D | HOH752 |
| D | HOH756 |
| D | HOH809 |
| D | HOH818 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue K D 604 |
| Chain | Residue |
| D | ASN69 |
| D | SER71 |
| D | ASP102 |
| D | THR103 |
| D | SER228 |
| D | ATP603 |
| D | HOH738 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue OXL D 605 |
| Chain | Residue |
| D | LYS255 |
| D | GLU257 |
| D | ALA278 |
| D | ARG279 |
| D | GLY280 |
| D | ASP281 |
| D | THR313 |
| D | MG601 |
| D | ATP603 |
| D | HOH712 |
| D | HOH742 |
| D | HOH809 |
Functional Information from PROSITE/UniProt
| site_id | PS00110 |
| Number of Residues | 13 |
| Details | PYRUVATE_KINASE Pyruvate kinase active site signature. IkIIPKIENiEGI |
| Chain | Residue | Details |
| A | ILE250-ILE262 | |
