6KR5
Crystal structure of O-Acetyl Serine Sulfhydrylase isoform 3 from Entamoeba histolytica
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | LYS58 |
| A | GLY236 |
| A | ILE237 |
| A | SER280 |
| A | PRO307 |
| A | ASP308 |
| A | TYR313 |
| A | HOH535 |
| A | HOH578 |
| A | HOH579 |
| A | HOH626 |
| A | ASN88 |
| A | ALA190 |
| A | VAL191 |
| A | GLY192 |
| A | THR193 |
| A | ALA194 |
| A | GLY195 |
| A | THR196 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 58 |
| Chain | Residue |
| B | SER56 |
| B | VAL57 |
| B | ASP59 |
| B | ARG60 |
| B | VAL61 |
| B | GLY62 |
| B | ASN88 |
| B | THR89 |
| B | GLY92 |
| B | ALA190 |
| B | VAL191 |
| B | GLY192 |
| B | THR193 |
| B | ALA194 |
| B | GLY195 |
| B | THR196 |
| B | GLY236 |
| B | ILE237 |
| B | SER280 |
| B | PRO307 |
| B | ASP308 |
| B | TYR313 |
| B | HOH568 |
| B | HOH574 |
| B | HOH649 |
| B | HOH743 |
