6KR2
Crystal structure of Dengue virus nonstructural protein NS5 (form 1)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
A | 0004483 | molecular_function | mRNA (nucleoside-2'-O-)-methyltransferase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0032259 | biological_process | methylation |
A | 0039694 | biological_process | viral RNA genome replication |
B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
B | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
B | 0004483 | molecular_function | mRNA (nucleoside-2'-O-)-methyltransferase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0008168 | molecular_function | methyltransferase activity |
B | 0032259 | biological_process | methylation |
B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 2001 |
Chain | Residue |
A | HIS712 |
A | HIS714 |
A | CYS728 |
A | CYS847 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ZN A 2002 |
Chain | Residue |
A | GLU438 |
A | HIS442 |
A | CYS447 |
A | CYS450 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue SAH A 2003 |
Chain | Residue |
A | GLY81 |
A | CYS82 |
A | TRP87 |
A | THR104 |
A | LYS105 |
A | HIS110 |
A | GLU111 |
A | VAL130 |
A | ASP131 |
A | VAL132 |
A | PHE133 |
A | ASP146 |
A | SER56 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1001 |
Chain | Residue |
B | GLU438 |
B | HIS442 |
B | CYS447 |
B | CYS450 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1002 |
Chain | Residue |
B | HIS712 |
B | HIS714 |
B | CYS728 |
B | CYS847 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue SAH B 1003 |
Chain | Residue |
B | SER56 |
B | GLY81 |
B | CYS82 |
B | GLY83 |
B | GLY86 |
B | TRP87 |
B | LYS105 |
B | HIS110 |
B | VAL130 |
B | VAL132 |
B | PHE133 |
B | ASP146 |