Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6KR1

ATP dependent protease HslV from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0003824	molecular_function	catalytic activity
A	0004298	molecular_function	threonine-type endopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0005839	cellular_component	proteasome core complex
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0009376	cellular_component	HslUV protease complex
A	0016787	molecular_function	hydrolase activity
A	0030163	biological_process	protein catabolic process
A	0046872	molecular_function	metal ion binding
A	0051603	biological_process	proteolysis involved in protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0003824	molecular_function	catalytic activity
B	0004298	molecular_function	threonine-type endopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0005839	cellular_component	proteasome core complex
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0009376	cellular_component	HslUV protease complex
B	0016787	molecular_function	hydrolase activity
B	0030163	biological_process	protein catabolic process
B	0046872	molecular_function	metal ion binding
B	0051603	biological_process	proteolysis involved in protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0003824	molecular_function	catalytic activity
C	0004298	molecular_function	threonine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0005839	cellular_component	proteasome core complex
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0009376	cellular_component	HslUV protease complex
C	0016787	molecular_function	hydrolase activity
C	0030163	biological_process	protein catabolic process
C	0046872	molecular_function	metal ion binding
C	0051603	biological_process	proteolysis involved in protein catabolic process
D	0000502	cellular_component	proteasome complex
D	0003824	molecular_function	catalytic activity
D	0004298	molecular_function	threonine-type endopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0005839	cellular_component	proteasome core complex
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0009376	cellular_component	HslUV protease complex
D	0016787	molecular_function	hydrolase activity
D	0030163	biological_process	protein catabolic process
D	0046872	molecular_function	metal ion binding
D	0051603	biological_process	proteolysis involved in protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0003824	molecular_function	catalytic activity
E	0004298	molecular_function	threonine-type endopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0005839	cellular_component	proteasome core complex
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0009376	cellular_component	HslUV protease complex
E	0016787	molecular_function	hydrolase activity
E	0030163	biological_process	protein catabolic process
E	0046872	molecular_function	metal ion binding
E	0051603	biological_process	proteolysis involved in protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0003824	molecular_function	catalytic activity
F	0004298	molecular_function	threonine-type endopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0005839	cellular_component	proteasome core complex
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0009376	cellular_component	HslUV protease complex
F	0016787	molecular_function	hydrolase activity
F	0030163	biological_process	protein catabolic process
F	0046872	molecular_function	metal ion binding
F	0051603	biological_process	proteolysis involved in protein catabolic process
G	0000502	cellular_component	proteasome complex
G	0003824	molecular_function	catalytic activity
G	0004298	molecular_function	threonine-type endopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0005839	cellular_component	proteasome core complex
G	0006508	biological_process	proteolysis
G	0008233	molecular_function	peptidase activity
G	0009376	cellular_component	HslUV protease complex
G	0016787	molecular_function	hydrolase activity
G	0030163	biological_process	protein catabolic process
G	0046872	molecular_function	metal ion binding
G	0051603	biological_process	proteolysis involved in protein catabolic process
H	0000502	cellular_component	proteasome complex
H	0003824	molecular_function	catalytic activity
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0005839	cellular_component	proteasome core complex
H	0006508	biological_process	proteolysis
H	0008233	molecular_function	peptidase activity
H	0009376	cellular_component	HslUV protease complex
H	0016787	molecular_function	hydrolase activity
H	0030163	biological_process	protein catabolic process
H	0046872	molecular_function	metal ion binding
H	0051603	biological_process	proteolysis involved in protein catabolic process
I	0000502	cellular_component	proteasome complex
I	0003824	molecular_function	catalytic activity
I	0004298	molecular_function	threonine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0005839	cellular_component	proteasome core complex
I	0006508	biological_process	proteolysis
I	0008233	molecular_function	peptidase activity
I	0009376	cellular_component	HslUV protease complex
I	0016787	molecular_function	hydrolase activity
I	0030163	biological_process	protein catabolic process
I	0046872	molecular_function	metal ion binding
I	0051603	biological_process	proteolysis involved in protein catabolic process
J	0000502	cellular_component	proteasome complex
J	0003824	molecular_function	catalytic activity
J	0004298	molecular_function	threonine-type endopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0005839	cellular_component	proteasome core complex
J	0006508	biological_process	proteolysis
J	0008233	molecular_function	peptidase activity
J	0009376	cellular_component	HslUV protease complex
J	0016787	molecular_function	hydrolase activity
J	0030163	biological_process	protein catabolic process
J	0046872	molecular_function	metal ion binding
J	0051603	biological_process	proteolysis involved in protein catabolic process
K	0000502	cellular_component	proteasome complex
K	0003824	molecular_function	catalytic activity
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0005839	cellular_component	proteasome core complex
K	0006508	biological_process	proteolysis
K	0008233	molecular_function	peptidase activity
K	0009376	cellular_component	HslUV protease complex
K	0016787	molecular_function	hydrolase activity
K	0030163	biological_process	protein catabolic process
K	0046872	molecular_function	metal ion binding
K	0051603	biological_process	proteolysis involved in protein catabolic process
L	0000502	cellular_component	proteasome complex
L	0003824	molecular_function	catalytic activity
L	0004298	molecular_function	threonine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0005839	cellular_component	proteasome core complex
L	0006508	biological_process	proteolysis
L	0008233	molecular_function	peptidase activity
L	0009376	cellular_component	HslUV protease complex
L	0016787	molecular_function	hydrolase activity
L	0030163	biological_process	protein catabolic process
L	0046872	molecular_function	metal ion binding
L	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG15
E	ARG45

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 A 202

Chain	Residue
A	ALA56
A	ALA102
A	MET103
A	ILE131
A	GLY132
A	HOH324

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 D 201

Chain	Residue
D	ALA102
D	MET103
D	ILE131
D	GLY132
D	HOH323
D	ALA56

site_id	AC4
Number of Residues	2
Details	binding site for residue SO4 D 202

Chain	Residue
D	ARG15
D	HOH313

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 G 201

Chain	Residue
G	ARG15
G	HOH310
I	ARG45

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 G 202

Chain	Residue
G	ALA56
G	ALA102
G	MET103
G	ILE131
G	GLY132
G	HOH337

site_id	AC7
Number of Residues	7
Details	binding site for residue SO4 H 201

Chain	Residue
H	ALA56
H	ALA102
H	MET103
H	ILE131
H	GLY132
H	HOH309
H	HOH347

site_id	AC8
Number of Residues	1
Details	binding site for residue SO4 J 201

Chain	Residue
J	ARG15

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 K 201

Chain	Residue
K	LYS42
K	SER58
K	VAL59

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00248","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	31
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00248","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)