6KOY
Crystal structure of two domain M1 Zinc metallopeptidase E323A mutant bound to L-tryptophan amino acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016285 | molecular_function | alanyl aminopeptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016285 | molecular_function | alanyl aminopeptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue TRP A 501 |
| Chain | Residue |
| A | LEU163 |
| A | ZN502 |
| A | HOH672 |
| A | GLU165 |
| A | ALA301 |
| A | GLU303 |
| A | HIS322 |
| A | HIS326 |
| A | GLU345 |
| A | PHE391 |
| A | TYR396 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | HIS322 |
| A | HIS326 |
| A | GLU345 |
| A | TRP501 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue TRP B 501 |
| Chain | Residue |
| B | LEU147 |
| B | ILE149 |
| B | LEU163 |
| B | GLU165 |
| B | ALA301 |
| B | GLU303 |
| B | HIS322 |
| B | HIS326 |
| B | GLU345 |
| B | PHE391 |
| B | TYR396 |
| B | ZN502 |
| B | HOH690 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 502 |
| Chain | Residue |
| B | HIS322 |
| B | HIS326 |
| B | GLU345 |
| B | TRP501 |
