Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | PRO408 |
| A | GLN432 |
| A | LEU435 |
| B | ARG17 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | TYR33 |
| A | ALA34 |
| A | TYR239 |
| A | PG4509 |
| A | HOH776 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | GLY26 |
| A | GLU27 |
| A | THR160 |
| A | MET161 |
| A | EDO504 |
| A | HOH722 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | MET161 |
| A | ALA162 |
| A | EDO503 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ARG56 |
| A | LEU92 |
| A | ASP93 |
| A | ARG133 |
| A | EDO506 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | LEU92 |
| A | ASP93 |
| A | ALA94 |
| A | VAL129 |
| A | EDO505 |
| A | EDO507 |
| A | HOH610 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLY97 |
| A | GLU98 |
| A | THR100 |
| A | EDO506 |
| A | HOH610 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | ARG56 |
| A | MET87 |
| A | ASP91 |
| A | HOH665 |
| A | HOH817 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue PG4 A 509 |
| Chain | Residue |
| A | TYR33 |
| A | GLY240 |
| A | TYR241 |
| A | TYR260 |
| A | CYS288 |
| A | PRO289 |
| A | GLU290 |
| A | ILE291 |
| A | EDO502 |
| A | HOH745 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | ILE165 |
| B | PHE205 |
| B | THR261 |
| B | GLN262 |
| B | HOH879 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| A | ARG17 |
| B | PRO408 |
| B | HIS412 |
| B | GLN432 |
| B | HOH678 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | TYR33 |
| B | ALA34 |
| B | TYR239 |
| B | HOH804 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | VAL53 |
| B | MET161 |
| B | ALA162 |
| B | EDO505 |
| B | HOH816 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | MET87 |
| B | ALA88 |
| B | GLY164 |
| B | EDO504 |
| B | EDO506 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | MET87 |
| B | LYS167 |
| B | EDO505 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 B 507 |
| Chain | Residue |
| B | GLY240 |
| B | TYR260 |
| B | CYS288 |
| B | PRO289 |
| B | GLU290 |
| B | ILE291 |
| B | ASP297 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | TYR179 |
| C | THR261 |
| C | EDO504 |
| C | HOH701 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | TYR33 |
| C | ALA34 |
| C | TYR239 |
| C | EDO503 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | TYR33 |
| C | GLY240 |
| C | CYS288 |
| C | EDO502 |
| C | HOH615 |
| C | HOH628 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | PHE171 |
| C | PHE299 |
| C | EDO501 |
| C | ILE165 |
