Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0044423 | cellular_component | virion component |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004527 | molecular_function | exonuclease activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0006284 | biological_process | base-excision repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0042025 | cellular_component | host cell nucleus |
| B | 0044423 | cellular_component | virion component |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004527 | molecular_function | exonuclease activity |
| C | 0006281 | biological_process | DNA repair |
| C | 0006284 | biological_process | base-excision repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0030430 | cellular_component | host cell cytoplasm |
| C | 0042025 | cellular_component | host cell nucleus |
| C | 0044423 | cellular_component | virion component |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0004527 | molecular_function | exonuclease activity |
| D | 0006281 | biological_process | DNA repair |
| D | 0006284 | biological_process | base-excision repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0030430 | cellular_component | host cell cytoplasm |
| D | 0042025 | cellular_component | host cell nucleus |
| D | 0044423 | cellular_component | virion component |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS78 |
| A | HIS115 |
| A | GLU142 |
| A | MES304 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | GLU142 |
| A | ASP179 |
| A | HIS218 |
| A | GLU271 |
| A | MES304 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 303 |
| Chain | Residue |
| A | ASP179 |
| A | HIS182 |
| A | ASP231 |
| A | HIS233 |
| A | MES304 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue MES A 304 |
| Chain | Residue |
| A | HIS78 |
| A | HIS115 |
| A | GLU142 |
| A | ASP179 |
| A | HIS182 |
| A | ASP231 |
| A | HIS233 |
| A | GLU271 |
| A | ZN301 |
| A | ZN302 |
| A | ZN303 |
| F | DG16 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | HIS182 |
| B | ASP231 |
| B | HIS233 |
| B | MES304 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 302 |
| Chain | Residue |
| B | HIS78 |
| B | HIS115 |
| B | GLU142 |
| B | MES304 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 303 |
| Chain | Residue |
| B | GLU142 |
| B | ASP179 |
| B | HIS218 |
| B | GLU271 |
| B | MES304 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue MES B 304 |
| Chain | Residue |
| B | HIS78 |
| B | HIS115 |
| B | GLU142 |
| B | ASP179 |
| B | HIS182 |
| B | ASP231 |
| B | HIS233 |
| B | GLU271 |
| B | ZN301 |
| B | ZN302 |
| B | ZN303 |
| G | DT17 |
| H | DG17 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 301 |
| Chain | Residue |
| C | HIS182 |
| C | ASP231 |
| C | HIS233 |
| C | MES304 |
| E | DG18 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN C 302 |
| Chain | Residue |
| C | GLU142 |
| C | ASP179 |
| C | HIS218 |
| C | GLU271 |
| C | ZN303 |
| C | MES304 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 303 |
| Chain | Residue |
| C | HIS78 |
| C | HIS115 |
| C | GLU142 |
| C | ZN302 |
| C | MES304 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue MES C 304 |
| Chain | Residue |
| C | HIS78 |
| C | HIS115 |
| C | GLU142 |
| C | HIS182 |
| C | HIS218 |
| C | ASP231 |
| C | HIS233 |
| C | GLU271 |
| C | ZN301 |
| C | ZN302 |
| C | ZN303 |
| E | DG18 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 301 |
| Chain | Residue |
| D | HIS182 |
| D | ASP231 |
| D | HIS233 |
| D | MES304 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue ZN D 302 |
| Chain | Residue |
| D | GLU142 |
| D | ASP179 |
| D | HIS218 |
| D | GLU271 |
| D | ZN303 |
| D | MES304 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 303 |
| Chain | Residue |
| D | HIS78 |
| D | HIS115 |
| D | GLU142 |
| D | ZN302 |
| D | MES304 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue MES D 304 |
| Chain | Residue |
| D | HIS182 |
| D | ASP231 |
| D | HIS233 |
| D | GLU271 |
| D | ZN301 |
| D | ZN302 |
| D | ZN303 |
| I | DC16 |
| J | DC18 |
| D | HIS78 |
| D | HIS115 |
| D | GLU142 |
| D | ASP179 |
Functional Information from PROSITE/UniProt
| site_id | PS00731 |
| Number of Residues | 17 |
| Details | AP_NUCLEASE_F2_3 AP endonucleases family 2 signature 3. FHlNDAatecGsgiDrH |
| Chain | Residue | Details |
| A | PHE217-HIS233 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32194979","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00763","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32194979","evidenceCode":"ECO:0000269"}]} |
