6KER

Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AA	0003824	molecular_function	catalytic activity
AA	0004364	molecular_function	glutathione transferase activity
AA	0004769	molecular_function	steroid delta-isomerase activity
AA	0005737	cellular_component	cytoplasm
AA	0006629	biological_process	lipid metabolic process
AA	0006694	biological_process	steroid biosynthetic process
AA	0006749	biological_process	glutathione metabolic process
AA	0009636	biological_process	response to toxic substance
AA	0016740	molecular_function	transferase activity
AA	0042632	biological_process	cholesterol homeostasis
AA	0045456	biological_process	ecdysteroid biosynthetic process
BA	0003824	molecular_function	catalytic activity
BA	0004364	molecular_function	glutathione transferase activity
BA	0004769	molecular_function	steroid delta-isomerase activity
BA	0005737	cellular_component	cytoplasm
BA	0006629	biological_process	lipid metabolic process
BA	0006694	biological_process	steroid biosynthetic process
BA	0006749	biological_process	glutathione metabolic process
BA	0009636	biological_process	response to toxic substance
BA	0016740	molecular_function	transferase activity
BA	0042632	biological_process	cholesterol homeostasis
BA	0045456	biological_process	ecdysteroid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue GSH AA 301

Chain	Residue
AA	SER14
AA	HIS71
AA	PHE110
AA	HOH446
AA	HOH464
BA	SER107
AA	LEU38
AA	GLN43
AA	HIS55
AA	SER56
AA	VAL57
AA	PRO58
AA	ASP69
AA	SER70

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site_id	AC2
Number of Residues	15
Details	binding site for residue GSH BA 301

Chain	Residue
AA	SER107
BA	SER14
BA	GLN43
BA	HIS55
BA	SER56
BA	VAL57
BA	PRO58
BA	ASP69
BA	SER70
BA	HIS71
BA	PHE110
BA	HOH415
BA	HOH434
BA	HOH440
BA	HOH453

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