6KER
Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AA | 0003824 | molecular_function | catalytic activity |
| AA | 0004364 | molecular_function | glutathione transferase activity |
| AA | 0004769 | molecular_function | steroid Delta-isomerase activity |
| AA | 0005737 | cellular_component | cytoplasm |
| AA | 0006749 | biological_process | glutathione metabolic process |
| AA | 0042632 | biological_process | cholesterol homeostasis |
| AA | 0045456 | biological_process | ecdysteroid biosynthetic process |
| BA | 0003824 | molecular_function | catalytic activity |
| BA | 0004364 | molecular_function | glutathione transferase activity |
| BA | 0004769 | molecular_function | steroid Delta-isomerase activity |
| BA | 0005737 | cellular_component | cytoplasm |
| BA | 0006749 | biological_process | glutathione metabolic process |
| BA | 0042632 | biological_process | cholesterol homeostasis |
| BA | 0045456 | biological_process | ecdysteroid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue GSH AA 301 |
| Chain | Residue |
| AA | SER14 |
| AA | HIS71 |
| AA | PHE110 |
| AA | HOH446 |
| AA | HOH464 |
| BA | SER107 |
| AA | LEU38 |
| AA | GLN43 |
| AA | HIS55 |
| AA | SER56 |
| AA | VAL57 |
| AA | PRO58 |
| AA | ASP69 |
| AA | SER70 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue GSH BA 301 |
| Chain | Residue |
| AA | SER107 |
| BA | SER14 |
| BA | GLN43 |
| BA | HIS55 |
| BA | SER56 |
| BA | VAL57 |
| BA | PRO58 |
| BA | ASP69 |
| BA | SER70 |
| BA | HIS71 |
| BA | PHE110 |
| BA | HOH415 |
| BA | HOH434 |
| BA | HOH440 |
| BA | HOH453 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 162 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 254 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
