Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0071797 | cellular_component | LUBAC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1101 |
| Chain | Residue |
| B | CYS871 |
| B | CYS874 |
| B | CYS890 |
| B | CYS893 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1102 |
| Chain | Residue |
| B | CYS898 |
| B | CYS901 |
| B | HIS926 |
| B | CYS930 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1103 |
| Chain | Residue |
| B | CYS916 |
| B | HIS923 |
| B | HIS925 |
| B | CYS911 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1104 |
| Chain | Residue |
| B | CYS969 |
| B | CYS986 |
| B | CYS998 |
| B | HIS1001 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue D5U B 1105 |
| Chain | Residue |
| B | GLY884 |
| B | CYS885 |
| B | MET886 |
| B | HIS887 |
| B | PHE905 |
| B | PHE932 |
| B | ARG935 |
| B | ASN949 |
| B | ASN950 |
| B | GLY1043 |
| B | GOL1108 |
| B | GOL1109 |
| B | HOH1215 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 1106 |
| Chain | Residue |
| B | GLU973 |
| B | LYS975 |
| B | ALA985 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1107 |
| Chain | Residue |
| B | TYR933 |
| B | TYR1021 |
| B | GLU1025 |
| B | THR1028 |
| B | ALA1029 |
| B | ARG1032 |
| B | TYR1033 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 1108 |
| Chain | Residue |
| B | ASN949 |
| B | HIS1013 |
| B | D5U1105 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 1109 |
| Chain | Residue |
| B | ASN950 |
| B | VAL951 |
| B | MET952 |
| B | HIS1013 |
| B | ARG1070 |
| B | D5U1105 |
| B | HOH1201 |
| B | HOH1215 |
| B | HOH1222 |
| B | HOH1237 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue EPE B 1110 |
| Chain | Residue |
| B | PRO872 |
| B | TYR902 |
| B | ASN903 |
| B | GLY968 |
| B | THR990 |
| B | GLY1064 |
| B | GLN1065 |
| B | SER1066 |
| B | HOH1218 |
| B | HOH1239 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CrHqFCsgCY |
| Chain | Residue | Details |
| B | CYS893-TYR902 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01221","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01221","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"(Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"27572974","evidenceCode":"ECO:0000269"}]} |
