6K8N

Crystal structure of the Sulfolobus solfataricus topoisomerase III

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003916	molecular_function	DNA topoisomerase activity
A	0003917	molecular_function	DNA topoisomerase type I (single strand cut, ATP-independent) activity
A	0006265	biological_process	DNA topological change
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0016853	molecular_function	isomerase activity
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
B	0003916	molecular_function	DNA topoisomerase activity
B	0003917	molecular_function	DNA topoisomerase type I (single strand cut, ATP-independent) activity
B	0006265	biological_process	DNA topological change
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0016853	molecular_function	isomerase activity
B	0046872	molecular_function	metal ion binding
C	0003677	molecular_function	DNA binding
C	0003916	molecular_function	DNA topoisomerase activity
C	0003917	molecular_function	DNA topoisomerase type I (single strand cut, ATP-independent) activity
C	0006265	biological_process	DNA topological change
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0016853	molecular_function	isomerase activity
C	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
D	0003916	molecular_function	DNA topoisomerase activity
D	0003917	molecular_function	DNA topoisomerase type I (single strand cut, ATP-independent) activity
D	0006265	biological_process	DNA topological change
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0016853	molecular_function	isomerase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 801

Chain	Residue
A	CYS602
A	CYS605
A	CYS615
A	HIS618

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 801

Chain	Residue
B	CYS602
B	CYS605
B	CYS615
B	HIS618

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN C 801

Chain	Residue
C	CYS605
C	CYS615
C	HIS618
C	CYS602

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 801

Chain	Residue
D	CYS602
D	CYS605
D	CYS615
D	HIS618

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1672
Details	Domain: {"description":"Topo IA-type catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01383","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"O-(5'-phospho-DNA)-tyrosine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU01383","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PDB","id":"6K8N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6K8O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---