6K8N
Crystal structure of the Sulfolobus solfataricus topoisomerase III
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003916 | molecular_function | DNA topoisomerase activity |
| A | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003916 | molecular_function | DNA topoisomerase activity |
| B | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003916 | molecular_function | DNA topoisomerase activity |
| C | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003916 | molecular_function | DNA topoisomerase activity |
| D | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | CYS602 |
| A | CYS605 |
| A | CYS615 |
| A | HIS618 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | CYS602 |
| B | CYS605 |
| B | CYS615 |
| B | HIS618 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 801 |
| Chain | Residue |
| C | CYS605 |
| C | CYS615 |
| C | HIS618 |
| C | CYS602 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 801 |
| Chain | Residue |
| D | CYS602 |
| D | CYS605 |
| D | CYS615 |
| D | HIS618 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1672 |
| Details | Domain: {"description":"Topo IA-type catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01383","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"O-(5'-phospho-DNA)-tyrosine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU01383","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"6K8N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6K8O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
