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6K81

Crystal structure of human VASH1-SVBP complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0001937biological_processnegative regulation of endothelial cell proliferation
A0003779molecular_functionactin binding
A0004180molecular_functioncarboxypeptidase activity
A0004181molecular_functionmetallocarboxypeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0006508biological_processproteolysis
A0009611biological_processresponse to wounding
A0016525biological_processnegative regulation of angiogenesis
A0043537biological_processnegative regulation of blood vessel endothelial cell migration
A0045177cellular_componentapical part of cell
A0045765biological_processregulation of angiogenesis
A0051726biological_processregulation of cell cycle
A0060674biological_processplacenta blood vessel development
A0060716biological_processlabyrinthine layer blood vessel development
A0106423molecular_functiontubulin-tyrosine carboxypeptidase
A1901491biological_processnegative regulation of lymphangiogenesis
A2000772biological_processregulation of cellular senescence
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0006508biological_processproteolysis
B0008017molecular_functionmicrotubule binding
B0009306biological_processprotein secretion
B0010596biological_processnegative regulation of endothelial cell migration
B0016504molecular_functionpeptidase activator activity
B0031397biological_processnegative regulation of protein ubiquitination
B0045177cellular_componentapical part of cell
B0061564biological_processaxon development
B1905048biological_processregulation of metallopeptidase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:29146869, ECO:0000305|PubMed:26794318
ChainResidueDetails
ACYS169

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:26794318
ChainResidueDetails
AHIS204
ASER221

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Cleavage => ECO:0000305|PubMed:16488400
ChainResidueDetails
AARG29
AARG76

223166

PDB entries from 2024-07-31

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