6K37
Crystal structure of BioU (K124A) from Synechocystis sp.PCC6803 in complex with NAD+ and the analog of reaction intermediate, 3-(1-aminoethyl)-nonanedioic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009102 | biological_process | biotin biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | GLY15 |
| A | PRO96 |
| A | ASN97 |
| A | PHE102 |
| A | ALA122 |
| A | ALA152 |
| A | THR153 |
| A | PRO154 |
| A | TYR188 |
| A | ARG189 |
| A | ALA190 |
| A | PHE16 |
| A | THR191 |
| A | GLU194 |
| A | VAL297 |
| A | CWL402 |
| A | HOH505 |
| A | GLY17 |
| A | GLY18 |
| A | LEU19 |
| A | ASP40 |
| A | ARG41 |
| A | TYR60 |
| A | LEU95 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue CWL A 402 |
| Chain | Residue |
| A | ALA124 |
| A | ALA152 |
| A | THR153 |
| A | PHE178 |
| A | GLY179 |
| A | VAL180 |
| A | THR191 |
| A | ASP195 |
| A | LYS263 |
| A | THR267 |
| A | MET293 |
| A | ASN296 |
| A | NAD401 |
| A | HOH510 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00852","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32042199","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00852","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32042199","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor and proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00852","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32042199","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00852","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32042199","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6K37","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Allysine","evidences":[{"source":"HAMAP-Rule","id":"MF_00852","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32042199","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
