6K05
Crystal structure of BRD2(BD1)with ligand BY27 bound
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue CQF A 201 |
| Chain | Residue |
| A | PRO98 |
| A | PHE99 |
| A | LYS107 |
| A | LEU108 |
| A | LEU110 |
| A | ASN156 |
| A | HOH311 |
| B | GLN94 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue CQF B 201 |
| Chain | Residue |
| B | TRP97 |
| B | PRO98 |
| B | PHE99 |
| B | LEU108 |
| B | LEU110 |
| B | ASN156 |
| B | HOH308 |
| A | GLN94 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MES B 202 |
| Chain | Residue |
| B | TRP97 |
| B | ARG100 |
| B | HOH342 |
| C | ARG128 |
| C | ASN132 |
| C | TYR134 |
| C | HOH221 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37731000","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SB6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20048151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2DVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DVS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
