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6JZD

Crystal structure of peptide-bound VASH2-SVBP complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000768biological_processsyncytium formation by plasma membrane fusion
A0001938biological_processpositive regulation of endothelial cell proliferation
A0003779molecular_functionactin binding
A0004180molecular_functioncarboxypeptidase activity
A0004181molecular_functionmetallocarboxypeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0006508biological_processproteolysis
A0008017molecular_functionmicrotubule binding
A0045765biological_processregulation of angiogenesis
A0045766biological_processpositive regulation of angiogenesis
A0060674biological_processplacenta blood vessel development
A0060711biological_processlabyrinthine layer development
A0060716biological_processlabyrinthine layer blood vessel development
A0061564biological_processaxon development
A0106423molecular_functiontubulin-tyrosine carboxypeptidase
A0140253biological_processcell-cell fusion
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0006508biological_processproteolysis
B0008017molecular_functionmicrotubule binding
B0009306biological_processprotein secretion
B0010596biological_processnegative regulation of endothelial cell migration
B0016504molecular_functionpeptidase activator activity
B0031397biological_processnegative regulation of protein ubiquitination
B0045177cellular_componentapical part of cell
B0061564biological_processaxon development
B1905048biological_processregulation of metallopeptidase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Involved in polymerization
ChainResidueDetails
CTYR15

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68373
ChainResidueDetails
CSER3
ASER210

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: 5-glutamyl polyglutamate => ECO:0000250|UniProtKB:Q71U36
ChainResidueDetails
CGLU7

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: 5-glutamyl polyglutamate => ECO:0000269|PubMed:1967194
ChainResidueDetails
CGLU9

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: 3'-nitrotyrosine => ECO:0000250|UniProtKB:Q71U36
ChainResidueDetails
CTYR15

222415

PDB entries from 2024-07-10

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