6JUZ
Crystal Structure of N-terminal domain of ArgZ(N71S) covalently bond to a reaction intermediate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue ARG A 301 |
| Chain | Residue |
| A | ILE21 |
| A | HIS168 |
| A | ASP170 |
| A | ALA258 |
| A | CYS264 |
| A | HOH401 |
| A | HOH402 |
| A | ASN22 |
| A | MET25 |
| A | ASP65 |
| A | PHE68 |
| A | ARG90 |
| A | GLY121 |
| A | ARG139 |
| A | TYR167 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ASP126 |
| A | ARG127 |
| A | TRP133 |
| A | PRO175 |
| A | LEU176 |
| A | GLY179 |
| A | TYR180 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | GLU39 |
| A | GLN40 |
| A | LYS43 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ARG127 |
| A | SER177 |
| A | ASN222 |
| A | VAL223 |
| A | ASN224 |
| A | ARG268 |
| A | HOH425 |
| A | HOH427 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ILE21 |
| A | PRO23 |
| A | ARG139 |
| A | GLU164 |
| A | TYR167 |
| A | HOH436 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | TYR136 |
| A | GLY137 |
| A | GLU141 |
| A | LEU142 |
| A | HOH514 |
| A | HOH553 |
| A | HOH585 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLY27 |
| A | ASN28 |
| A | ILE29 |
| A | HOH528 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | PRO23 |
| A | TRP24 |
| A | ARG165 |
| A | HOH509 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | TRP151 |
| A | LEU211 |
| A | ASP212 |
| A | ASN215 |
| A | SER233 |
| A | HOH414 |
| A | HOH472 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | SER177 |
| A | GLY178 |
| A | ALA243 |
| A | PHE245 |
| A | HOH535 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | PHE125 |
| A | GLY129 |
| A | GLU271 |
| A | PRO272 |
| A | HOH443 |
| A | HOH506 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 259 |
| Details | Region: {"description":"Arginine dihydrolase","evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6JV0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6JUZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6JV1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Key determinant for dihydrolase activity","evidences":[{"source":"PubMed","id":"31914412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
