6JTK
Crystal structure of NagZ from Neisseria gonorrhoeae in complex with N-trifluoroacetyl-D-glucosamine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009254 | biological_process | peptidoglycan turnover |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009254 | biological_process | peptidoglycan turnover |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009254 | biological_process | peptidoglycan turnover |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009254 | biological_process | peptidoglycan turnover |
| E | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| E | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0009254 | biological_process | peptidoglycan turnover |
| F | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| F | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0009254 | biological_process | peptidoglycan turnover |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue C76 A 401 |
| Chain | Residue |
| A | ILE37 |
| C | ASP185 |
| C | SER186 |
| A | ASP69 |
| A | ILE141 |
| A | ARG144 |
| A | LYS174 |
| A | HIS175 |
| A | HIS179 |
| A | ASP258 |
| A | HOH526 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue C76 B 401 |
| Chain | Residue |
| B | ASP69 |
| B | ILE141 |
| B | ARG144 |
| B | LYS174 |
| B | HIS175 |
| B | HIS179 |
| B | HOH508 |
| B | HOH551 |
| B | HOH641 |
| B | HOH650 |
| B | HOH662 |
| F | ASP185 |
| F | SER186 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue C76 C 401 |
| Chain | Residue |
| A | ASP185 |
| C | ASP69 |
| C | ILE141 |
| C | ARG144 |
| C | LYS174 |
| C | HIS175 |
| C | HIS179 |
| C | HOH510 |
| C | HOH523 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue C76 D 401 |
| Chain | Residue |
| D | ILE37 |
| D | ASP69 |
| D | ILE141 |
| D | ARG144 |
| D | LYS174 |
| D | HIS175 |
| D | HIS179 |
| D | HOH529 |
| E | ASP185 |
| E | SER186 |
Functional Information from PROSITE/UniProt
| site_id | PS00775 |
| Number of Residues | 18 |
| Details | GLYCOSYL_HYDROL_F3 Glycosyl hydrolases family 3 active site. ILRrDigfkGVIFSDdlT |
| Chain | Residue | Details |
| A | ILE244-THR261 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00364","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00364","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"HAMAP-Rule","id":"MF_00364","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00364","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
