6JON
Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue DTP A 401 |
| Chain | Residue |
| A | LYS27 |
| A | TYR146 |
| A | MET147 |
| A | THR148 |
| A | MG402 |
| A | ASP78 |
| A | ASP80 |
| A | SER108 |
| A | PRO109 |
| A | SER110 |
| A | ASP112 |
| A | HIS115 |
| A | ARG145 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | ASP78 |
| A | ASP80 |
| A | DTP401 |
| A | HOH506 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | THR69 |
| A | ASP72 |
| A | PHE74 |
| A | GLU142 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 175 |
| Details | Region: {"description":"Polymerase","evidences":[{"source":"PubMed","id":"32016421","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For polymerase activity","evidences":[{"source":"PubMed","id":"28265063","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For polymerase and primase activities","evidences":[{"source":"PubMed","id":"30739783","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31176489","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34975792","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31176489","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in primer extension","evidences":[{"source":"PubMed","id":"31176489","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in sugar discrimination to select deoxynucleotides","evidences":[{"source":"PubMed","id":"31176489","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
