6JN2

Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0031151	molecular_function	histone H3K79 methyltransferase activity
B	0051726	biological_process	regulation of cell cycle

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
B	SER471

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
B	THR480

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