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6J2Q

Yeast proteasome in Ub-accepted state (C1-b)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
10000502cellular_componentproteasome complex
10004175molecular_functionendopeptidase activity
10004298molecular_functionthreonine-type endopeptidase activity
10005634cellular_componentnucleus
10005737cellular_componentcytoplasm
10005829cellular_componentcytosol
10005839cellular_componentproteasome core complex
10006508biological_processproteolysis
10008233molecular_functionpeptidase activity
10010499biological_processproteasomal ubiquitin-independent protein catabolic process
10016787molecular_functionhydrolase activity
10019774cellular_componentproteasome core complex, beta-subunit complex
10034515cellular_componentproteasome storage granule
10043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
10051603biological_processproteolysis involved in protein catabolic process
20000502cellular_componentproteasome complex
20004175molecular_functionendopeptidase activity
20004298molecular_functionthreonine-type endopeptidase activity
20005515molecular_functionprotein binding
20005634cellular_componentnucleus
20005737cellular_componentcytoplasm
20005829cellular_componentcytosol
20005839cellular_componentproteasome core complex
20006508biological_processproteolysis
20008233molecular_functionpeptidase activity
20010499biological_processproteasomal ubiquitin-independent protein catabolic process
20016787molecular_functionhydrolase activity
20019774cellular_componentproteasome core complex, beta-subunit complex
20034515cellular_componentproteasome storage granule
20043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
20051603biological_processproteolysis involved in protein catabolic process
30000502cellular_componentproteasome complex
30005515molecular_functionprotein binding
30005634cellular_componentnucleus
30005737cellular_componentcytoplasm
30005829cellular_componentcytosol
30005839cellular_componentproteasome core complex
30010499biological_processproteasomal ubiquitin-independent protein catabolic process
30019774cellular_componentproteasome core complex, beta-subunit complex
30043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
30051603biological_processproteolysis involved in protein catabolic process
30061133molecular_functionendopeptidase activator activity
40000502cellular_componentproteasome complex
40005515molecular_functionprotein binding
40005634cellular_componentnucleus
40005737cellular_componentcytoplasm
40005789cellular_componentendoplasmic reticulum membrane
40005829cellular_componentcytosol
40005839cellular_componentproteasome core complex
40010498biological_processproteasomal protein catabolic process
40010499biological_processproteasomal ubiquitin-independent protein catabolic process
40019774cellular_componentproteasome core complex, beta-subunit complex
40043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
40051603biological_processproteolysis involved in protein catabolic process
40061133molecular_functionendopeptidase activator activity
50000502cellular_componentproteasome complex
50004175molecular_functionendopeptidase activity
50004298molecular_functionthreonine-type endopeptidase activity
50005515molecular_functionprotein binding
50005634cellular_componentnucleus
50005737cellular_componentcytoplasm
50005829cellular_componentcytosol
50005839cellular_componentproteasome core complex
50006508biological_processproteolysis
50008233molecular_functionpeptidase activity
50010499biological_processproteasomal ubiquitin-independent protein catabolic process
50016787molecular_functionhydrolase activity
50019774cellular_componentproteasome core complex, beta-subunit complex
50043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
50051603biological_processproteolysis involved in protein catabolic process
50080129biological_processproteasome core complex assembly
60000502cellular_componentproteasome complex
60003674molecular_functionmolecular_function
60005515molecular_functionprotein binding
60005634cellular_componentnucleus
60005737cellular_componentcytoplasm
60005829cellular_componentcytosol
60005839cellular_componentproteasome core complex
60010499biological_processproteasomal ubiquitin-independent protein catabolic process
60019774cellular_componentproteasome core complex, beta-subunit complex
60043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
60051603biological_processproteolysis involved in protein catabolic process
70000502cellular_componentproteasome complex
70003674molecular_functionmolecular_function
70005515molecular_functionprotein binding
70005634cellular_componentnucleus
70005737cellular_componentcytoplasm
70005829cellular_componentcytosol
70005839cellular_componentproteasome core complex
70010499biological_processproteasomal ubiquitin-independent protein catabolic process
70019774cellular_componentproteasome core complex, beta-subunit complex
70034515cellular_componentproteasome storage granule
70043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
70043248biological_processproteasome assembly
70051603biological_processproteolysis involved in protein catabolic process
A0000502cellular_componentproteasome complex
A0003674molecular_functionmolecular_function
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005839cellular_componentproteasome core complex
A0006511biological_processubiquitin-dependent protein catabolic process
A0010498biological_processproteasomal protein catabolic process
A0010499biological_processproteasomal ubiquitin-independent protein catabolic process
A0019773cellular_componentproteasome core complex, alpha-subunit complex
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0051603biological_processproteolysis involved in protein catabolic process
B0000502cellular_componentproteasome complex
B0003674molecular_functionmolecular_function
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005839cellular_componentproteasome core complex
B0006511biological_processubiquitin-dependent protein catabolic process
B0010498biological_processproteasomal protein catabolic process
B0010499biological_processproteasomal ubiquitin-independent protein catabolic process
B0019773cellular_componentproteasome core complex, alpha-subunit complex
B0034515cellular_componentproteasome storage granule
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0051603biological_processproteolysis involved in protein catabolic process
C0000502cellular_componentproteasome complex
C0003674molecular_functionmolecular_function
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005839cellular_componentproteasome core complex
C0006511biological_processubiquitin-dependent protein catabolic process
C0010498biological_processproteasomal protein catabolic process
C0010499biological_processproteasomal ubiquitin-independent protein catabolic process
C0019773cellular_componentproteasome core complex, alpha-subunit complex
C0034515cellular_componentproteasome storage granule
C0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0051603biological_processproteolysis involved in protein catabolic process
C0080129biological_processproteasome core complex assembly
D0000502cellular_componentproteasome complex
D0003674molecular_functionmolecular_function
D0004175molecular_functionendopeptidase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005829cellular_componentcytosol
D0005839cellular_componentproteasome core complex
D0006511biological_processubiquitin-dependent protein catabolic process
D0010498biological_processproteasomal protein catabolic process
D0010499biological_processproteasomal ubiquitin-independent protein catabolic process
D0019773cellular_componentproteasome core complex, alpha-subunit complex
D0019774cellular_componentproteasome core complex, beta-subunit complex
D0034515cellular_componentproteasome storage granule
D0042175cellular_componentnuclear outer membrane-endoplasmic reticulum membrane network
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
D0051603biological_processproteolysis involved in protein catabolic process
E0000502cellular_componentproteasome complex
E0003674molecular_functionmolecular_function
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005839cellular_componentproteasome core complex
E0006511biological_processubiquitin-dependent protein catabolic process
E0010498biological_processproteasomal protein catabolic process
E0010499biological_processproteasomal ubiquitin-independent protein catabolic process
E0019773cellular_componentproteasome core complex, alpha-subunit complex
E0034515cellular_componentproteasome storage granule
E0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
E0051603biological_processproteolysis involved in protein catabolic process
F0000502cellular_componentproteasome complex
F0003674molecular_functionmolecular_function
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005839cellular_componentproteasome core complex
F0006511biological_processubiquitin-dependent protein catabolic process
F0010498biological_processproteasomal protein catabolic process
F0010499biological_processproteasomal ubiquitin-independent protein catabolic process
F0019773cellular_componentproteasome core complex, alpha-subunit complex
F0034515cellular_componentproteasome storage granule
F0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
F0051603biological_processproteolysis involved in protein catabolic process
G0000502cellular_componentproteasome complex
G0003729molecular_functionmRNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005839cellular_componentproteasome core complex
G0006511biological_processubiquitin-dependent protein catabolic process
G0010498biological_processproteasomal protein catabolic process
G0010499biological_processproteasomal ubiquitin-independent protein catabolic process
G0019773cellular_componentproteasome core complex, alpha-subunit complex
G0034515cellular_componentproteasome storage granule
G0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
G0051603biological_processproteolysis involved in protein catabolic process
H0000166molecular_functionnucleotide binding
H0000502cellular_componentproteasome complex
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0006511biological_processubiquitin-dependent protein catabolic process
H0008540cellular_componentproteasome regulatory particle, base subcomplex
H0010604biological_processpositive regulation of macromolecule metabolic process
H0016887molecular_functionATP hydrolysis activity
H0031625molecular_functionubiquitin protein ligase binding
H0036402molecular_functionproteasome-activating activity
H0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
H0045732biological_processpositive regulation of protein catabolic process
H0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
H0051173biological_processpositive regulation of nitrogen compound metabolic process
H0070682biological_processproteasome regulatory particle assembly
H1901800biological_processpositive regulation of proteasomal protein catabolic process
I0000166molecular_functionnucleotide binding
I0000502cellular_componentproteasome complex
I0005515molecular_functionprotein binding
I0005524molecular_functionATP binding
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0006511biological_processubiquitin-dependent protein catabolic process
I0008540cellular_componentproteasome regulatory particle, base subcomplex
I0010604biological_processpositive regulation of macromolecule metabolic process
I0016887molecular_functionATP hydrolysis activity
I0031503biological_processprotein-containing complex localization
I0036402molecular_functionproteasome-activating activity
I0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
I0043171biological_processpeptide catabolic process
I0045732biological_processpositive regulation of protein catabolic process
I0051173biological_processpositive regulation of nitrogen compound metabolic process
I0070651biological_processnonfunctional rRNA decay
I0070682biological_processproteasome regulatory particle assembly
I1901800biological_processpositive regulation of proteasomal protein catabolic process
J0000166molecular_functionnucleotide binding
J0000502cellular_componentproteasome complex
J0005515molecular_functionprotein binding
J0005524molecular_functionATP binding
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0006289biological_processnucleotide-excision repair
J0006338biological_processchromatin remodeling
J0008540cellular_componentproteasome regulatory particle, base subcomplex
J0010604biological_processpositive regulation of macromolecule metabolic process
J0016887molecular_functionATP hydrolysis activity
J0019904molecular_functionprotein domain specific binding
J0031625molecular_functionubiquitin protein ligase binding
J0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
J0034515cellular_componentproteasome storage granule
J0036402molecular_functionproteasome-activating activity
J0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
J0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
J0051173biological_processpositive regulation of nitrogen compound metabolic process
J0070651biological_processnonfunctional rRNA decay
J0070682biological_processproteasome regulatory particle assembly
J1901800biological_processpositive regulation of proteasomal protein catabolic process
K0000166molecular_functionnucleotide binding
K0000502cellular_componentproteasome complex
K0005515molecular_functionprotein binding
K0005524molecular_functionATP binding
K0005634cellular_componentnucleus
K0005737cellular_componentcytoplasm
K0006511biological_processubiquitin-dependent protein catabolic process
K0008540cellular_componentproteasome regulatory particle, base subcomplex
K0010604biological_processpositive regulation of macromolecule metabolic process
K0016887molecular_functionATP hydrolysis activity
K0036402molecular_functionproteasome-activating activity
K0042802molecular_functionidentical protein binding
K0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
K0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
K0051173biological_processpositive regulation of nitrogen compound metabolic process
K0070682biological_processproteasome regulatory particle assembly
K1901800biological_processpositive regulation of proteasomal protein catabolic process
L0000166molecular_functionnucleotide binding
L0000502cellular_componentproteasome complex
L0005515molecular_functionprotein binding
L0005524molecular_functionATP binding
L0005634cellular_componentnucleus
L0006289biological_processnucleotide-excision repair
L0008540cellular_componentproteasome regulatory particle, base subcomplex
L0010604biological_processpositive regulation of macromolecule metabolic process
L0016887molecular_functionATP hydrolysis activity
L0019904molecular_functionprotein domain specific binding
L0031597cellular_componentcytosolic proteasome complex
L0031625molecular_functionubiquitin protein ligase binding
L0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
L0036402molecular_functionproteasome-activating activity
L0036503biological_processERAD pathway
L0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
L0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
L0051173biological_processpositive regulation of nitrogen compound metabolic process
L0070682biological_processproteasome regulatory particle assembly
L1901800biological_processpositive regulation of proteasomal protein catabolic process
M0000166molecular_functionnucleotide binding
M0000502cellular_componentproteasome complex
M0005515molecular_functionprotein binding
M0005524molecular_functionATP binding
M0005634cellular_componentnucleus
M0005737cellular_componentcytoplasm
M0006511biological_processubiquitin-dependent protein catabolic process
M0008540cellular_componentproteasome regulatory particle, base subcomplex
M0010604biological_processpositive regulation of macromolecule metabolic process
M0016887molecular_functionATP hydrolysis activity
M0036402molecular_functionproteasome-activating activity
M0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
M0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
M0051173biological_processpositive regulation of nitrogen compound metabolic process
M0070682biological_processproteasome regulatory particle assembly
M1901800biological_processpositive regulation of proteasomal protein catabolic process
N0000502cellular_componentproteasome complex
N0004175molecular_functionendopeptidase activity
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0006511biological_processubiquitin-dependent protein catabolic process
N0008540cellular_componentproteasome regulatory particle, base subcomplex
N0030234molecular_functionenzyme regulator activity
N0031625molecular_functionubiquitin protein ligase binding
N0034515cellular_componentproteasome storage granule
N0042176biological_processregulation of protein catabolic process
N0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
N0043248biological_processproteasome assembly
O0000502cellular_componentproteasome complex
O0005198molecular_functionstructural molecule activity
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005829cellular_componentcytosol
O0006511biological_processubiquitin-dependent protein catabolic process
O0008541cellular_componentproteasome regulatory particle, lid subcomplex
O0034515cellular_componentproteasome storage granule
O0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
O0043248biological_processproteasome assembly
P0000338biological_processprotein deneddylation
P0000502cellular_componentproteasome complex
P0005515molecular_functionprotein binding
P0005737cellular_componentcytoplasm
P0008180cellular_componentCOP9 signalosome
P0008541cellular_componentproteasome regulatory particle, lid subcomplex
P0034515cellular_componentproteasome storage granule
P0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0000502cellular_componentproteasome complex
Q0005198molecular_functionstructural molecule activity
Q0005515molecular_functionprotein binding
Q0006511biological_processubiquitin-dependent protein catabolic process
Q0008541cellular_componentproteasome regulatory particle, lid subcomplex
Q0034515cellular_componentproteasome storage granule
Q0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0043248biological_processproteasome assembly
R0000502cellular_componentproteasome complex
R0005198molecular_functionstructural molecule activity
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005838cellular_componentproteasome regulatory particle
R0006511biological_processubiquitin-dependent protein catabolic process
R0008541cellular_componentproteasome regulatory particle, lid subcomplex
R0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
S0000502cellular_componentproteasome complex
S0003674molecular_functionmolecular_function
S0005515molecular_functionprotein binding
S0006511biological_processubiquitin-dependent protein catabolic process
S0008541cellular_componentproteasome regulatory particle, lid subcomplex
S0030234molecular_functionenzyme regulator activity
S0042176biological_processregulation of protein catabolic process
S0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
T0000502cellular_componentproteasome complex
T0003674molecular_functionmolecular_function
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005829cellular_componentcytosol
T0005838cellular_componentproteasome regulatory particle
T0006508biological_processproteolysis
T0006511biological_processubiquitin-dependent protein catabolic process
T0008541cellular_componentproteasome regulatory particle, lid subcomplex
T0034515cellular_componentproteasome storage granule
T0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
U0000502cellular_componentproteasome complex
U0005515molecular_functionprotein binding
U0005838cellular_componentproteasome regulatory particle
U0006511biological_processubiquitin-dependent protein catabolic process
U0008233molecular_functionpeptidase activity
U0008237molecular_functionmetallopeptidase activity
U0008541cellular_componentproteasome regulatory particle, lid subcomplex
U0034515cellular_componentproteasome storage granule
U0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0000266biological_processmitochondrial fission
V0000502cellular_componentproteasome complex
V0004843molecular_functioncysteine-type deubiquitinase activity
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005739cellular_componentmitochondrion
V0005829cellular_componentcytosol
V0006508biological_processproteolysis
V0008233molecular_functionpeptidase activity
V0008234molecular_functioncysteine-type peptidase activity
V0008237molecular_functionmetallopeptidase activity
V0008270molecular_functionzinc ion binding
V0008541cellular_componentproteasome regulatory particle, lid subcomplex
V0016559biological_processperoxisome fission
V0016579biological_processprotein deubiquitination
V0016787molecular_functionhydrolase activity
V0034515cellular_componentproteasome storage granule
V0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0043248biological_processproteasome assembly
V0046872molecular_functionmetal ion binding
V0070628molecular_functionproteasome binding
V0140492molecular_functionmetal-dependent deubiquitinase activity
V1902906biological_processproteasome storage granule assembly
W0000502cellular_componentproteasome complex
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005829cellular_componentcytosol
W0006511biological_processubiquitin-dependent protein catabolic process
W0008540cellular_componentproteasome regulatory particle, base subcomplex
W0031593molecular_functionpolyubiquitin modification-dependent protein binding
W0036435molecular_functionK48-linked polyubiquitin modification-dependent protein binding
W0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
W0043248biological_processproteasome assembly
X0000502cellular_componentproteasome complex
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0006511biological_processubiquitin-dependent protein catabolic process
X0008541cellular_componentproteasome regulatory particle, lid subcomplex
X0034515cellular_componentproteasome storage granule
X0043130molecular_functionubiquitin binding
X0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
X0061133molecular_functionendopeptidase activator activity
X0070628molecular_functionproteasome binding
Y0000502cellular_componentproteasome complex
Y0000724biological_processdouble-strand break repair via homologous recombination
Y0003674molecular_functionmolecular_function
Y0005515molecular_functionprotein binding
Y0005829cellular_componentcytosol
Y0006406biological_processmRNA export from nucleus
Y0006457biological_processprotein folding
Y0006511biological_processubiquitin-dependent protein catabolic process
Y0008541cellular_componentproteasome regulatory particle, lid subcomplex
Y0030447biological_processfilamentous growth
Y0034515cellular_componentproteasome storage granule
Y0035753biological_processmaintenance of DNA trinucleotide repeats
Y0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Y0043248biological_processproteasome assembly
Y0044183molecular_functionprotein folding chaperone
Y0045944biological_processpositive regulation of transcription by RNA polymerase II
Y0051726biological_processregulation of cell cycle
Y0060090molecular_functionmolecular adaptor activity
Y0070390cellular_componenttranscription export complex 2
Y0072742biological_processSAGA complex localization to transcription regulatory region
Z0000502cellular_componentproteasome complex
Z0004175molecular_functionendopeptidase activity
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0005737cellular_componentcytoplasm
Z0005783cellular_componentendoplasmic reticulum
Z0006511biological_processubiquitin-dependent protein catabolic process
Z0008540cellular_componentproteasome regulatory particle, base subcomplex
Z0030234molecular_functionenzyme regulator activity
Z0030674molecular_functionprotein-macromolecule adaptor activity
Z0034515cellular_componentproteasome storage granule
Z0042176biological_processregulation of protein catabolic process
Z0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0000502cellular_componentproteasome complex
a0003674molecular_functionmolecular_function
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005839cellular_componentproteasome core complex
a0010499biological_processproteasomal ubiquitin-independent protein catabolic process
a0019774cellular_componentproteasome core complex, beta-subunit complex
a0034515cellular_componentproteasome storage granule
a0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0043248biological_processproteasome assembly
a0051603biological_processproteolysis involved in protein catabolic process
b0000502cellular_componentproteasome complex
b0004175molecular_functionendopeptidase activity
b0004298molecular_functionthreonine-type endopeptidase activity
b0005634cellular_componentnucleus
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005839cellular_componentproteasome core complex
b0006508biological_processproteolysis
b0008233molecular_functionpeptidase activity
b0010499biological_processproteasomal ubiquitin-independent protein catabolic process
b0016787molecular_functionhydrolase activity
b0019774cellular_componentproteasome core complex, beta-subunit complex
b0034515cellular_componentproteasome storage granule
b0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
b0051603biological_processproteolysis involved in protein catabolic process
c0000502cellular_componentproteasome complex
c0003674molecular_functionmolecular_function
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005737cellular_componentcytoplasm
c0005739cellular_componentmitochondrion
c0005829cellular_componentcytosol
c0005839cellular_componentproteasome core complex
c0006511biological_processubiquitin-dependent protein catabolic process
c0010498biological_processproteasomal protein catabolic process
c0010499biological_processproteasomal ubiquitin-independent protein catabolic process
c0019773cellular_componentproteasome core complex, alpha-subunit complex
c0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
c0051603biological_processproteolysis involved in protein catabolic process
d0000502cellular_componentproteasome complex
d0003674molecular_functionmolecular_function
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005737cellular_componentcytoplasm
d0005829cellular_componentcytosol
d0005839cellular_componentproteasome core complex
d0006511biological_processubiquitin-dependent protein catabolic process
d0010498biological_processproteasomal protein catabolic process
d0010499biological_processproteasomal ubiquitin-independent protein catabolic process
d0019773cellular_componentproteasome core complex, alpha-subunit complex
d0034515cellular_componentproteasome storage granule
d0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
d0051603biological_processproteolysis involved in protein catabolic process
d0080129biological_processproteasome core complex assembly
e0000502cellular_componentproteasome complex
e0003674molecular_functionmolecular_function
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005737cellular_componentcytoplasm
e0005829cellular_componentcytosol
e0005839cellular_componentproteasome core complex
e0010499biological_processproteasomal ubiquitin-independent protein catabolic process
e0019774cellular_componentproteasome core complex, beta-subunit complex
e0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
e0051603biological_processproteolysis involved in protein catabolic process
f0000502cellular_componentproteasome complex
f0004175molecular_functionendopeptidase activity
f0004298molecular_functionthreonine-type endopeptidase activity
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005737cellular_componentcytoplasm
f0005829cellular_componentcytosol
f0005839cellular_componentproteasome core complex
f0006508biological_processproteolysis
f0008233molecular_functionpeptidase activity
f0010499biological_processproteasomal ubiquitin-independent protein catabolic process
f0016787molecular_functionhydrolase activity
f0019774cellular_componentproteasome core complex, beta-subunit complex
f0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
f0051603biological_processproteolysis involved in protein catabolic process
f0080129biological_processproteasome core complex assembly
g0000502cellular_componentproteasome complex
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005737cellular_componentcytoplasm
g0005789cellular_componentendoplasmic reticulum membrane
g0005829cellular_componentcytosol
g0005839cellular_componentproteasome core complex
g0010498biological_processproteasomal protein catabolic process
g0010499biological_processproteasomal ubiquitin-independent protein catabolic process
g0019774cellular_componentproteasome core complex, beta-subunit complex
g0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
g0051603biological_processproteolysis involved in protein catabolic process
g0061133molecular_functionendopeptidase activator activity
h0000502cellular_componentproteasome complex
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005737cellular_componentcytoplasm
h0005829cellular_componentcytosol
h0005839cellular_componentproteasome core complex
h0010499biological_processproteasomal ubiquitin-independent protein catabolic process
h0019774cellular_componentproteasome core complex, beta-subunit complex
h0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
h0051603biological_processproteolysis involved in protein catabolic process
h0061133molecular_functionendopeptidase activator activity
i0000502cellular_componentproteasome complex
i0004175molecular_functionendopeptidase activity
i0004298molecular_functionthreonine-type endopeptidase activity
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005737cellular_componentcytoplasm
i0005829cellular_componentcytosol
i0005839cellular_componentproteasome core complex
i0006508biological_processproteolysis
i0008233molecular_functionpeptidase activity
i0010499biological_processproteasomal ubiquitin-independent protein catabolic process
i0016787molecular_functionhydrolase activity
i0019774cellular_componentproteasome core complex, beta-subunit complex
i0034515cellular_componentproteasome storage granule
i0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
i0051603biological_processproteolysis involved in protein catabolic process
j0000502cellular_componentproteasome complex
j0003674molecular_functionmolecular_function
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005737cellular_componentcytoplasm
j0005839cellular_componentproteasome core complex
j0006511biological_processubiquitin-dependent protein catabolic process
j0010498biological_processproteasomal protein catabolic process
j0010499biological_processproteasomal ubiquitin-independent protein catabolic process
j0019773cellular_componentproteasome core complex, alpha-subunit complex
j0034515cellular_componentproteasome storage granule
j0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
j0051603biological_processproteolysis involved in protein catabolic process
k0000502cellular_componentproteasome complex
k0003729molecular_functionmRNA binding
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005737cellular_componentcytoplasm
k0005839cellular_componentproteasome core complex
k0006511biological_processubiquitin-dependent protein catabolic process
k0010498biological_processproteasomal protein catabolic process
k0010499biological_processproteasomal ubiquitin-independent protein catabolic process
k0019773cellular_componentproteasome core complex, alpha-subunit complex
k0034515cellular_componentproteasome storage granule
k0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
k0051603biological_processproteolysis involved in protein catabolic process
l0000502cellular_componentproteasome complex
l0003674molecular_functionmolecular_function
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005737cellular_componentcytoplasm
l0005839cellular_componentproteasome core complex
l0006511biological_processubiquitin-dependent protein catabolic process
l0010498biological_processproteasomal protein catabolic process
l0010499biological_processproteasomal ubiquitin-independent protein catabolic process
l0019773cellular_componentproteasome core complex, alpha-subunit complex
l0034515cellular_componentproteasome storage granule
l0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
l0051603biological_processproteolysis involved in protein catabolic process
m0000502cellular_componentproteasome complex
m0003674molecular_functionmolecular_function
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005737cellular_componentcytoplasm
m0005839cellular_componentproteasome core complex
m0006511biological_processubiquitin-dependent protein catabolic process
m0010498biological_processproteasomal protein catabolic process
m0010499biological_processproteasomal ubiquitin-independent protein catabolic process
m0019773cellular_componentproteasome core complex, alpha-subunit complex
m0034515cellular_componentproteasome storage granule
m0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
m0051603biological_processproteolysis involved in protein catabolic process
n0000502cellular_componentproteasome complex
n0003674molecular_functionmolecular_function
n0004175molecular_functionendopeptidase activity
n0005515molecular_functionprotein binding
n0005634cellular_componentnucleus
n0005737cellular_componentcytoplasm
n0005739cellular_componentmitochondrion
n0005829cellular_componentcytosol
n0005839cellular_componentproteasome core complex
n0006511biological_processubiquitin-dependent protein catabolic process
n0010498biological_processproteasomal protein catabolic process
n0010499biological_processproteasomal ubiquitin-independent protein catabolic process
n0019773cellular_componentproteasome core complex, alpha-subunit complex
n0019774cellular_componentproteasome core complex, beta-subunit complex
n0034515cellular_componentproteasome storage granule
n0042175cellular_componentnuclear outer membrane-endoplasmic reticulum membrane network
n0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
n0051603biological_processproteolysis involved in protein catabolic process
Functional Information from PROSITE/UniProt
site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DDDEIDV
ChainResidueDetails
UASP243-VAL249

site_idPS00388
Number of Residues23
DetailsPROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdrgvStFSPeGRlfQVEYSleA
ChainResidueDetails
ETYR8-ALA30
CTYR6-SER28
BTYR5-ALA27
DTYR4-ALA26
lTYR6-ALA28
ATYR12-ALA34
kTYR8-ALA30

site_idPS00854
Number of Residues48
DetailsPROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAVtFkdGVILGADsrtttgayianrvtd.KltrvhdkiwccrsGsaAD
ChainResidueDetails
1MET23-ASP70
CILE36-ASP83
2VAL33-ASP80
5LEU79-ASP126
DVAL34-ASP81
3VAL13-ASP59
6LEU32-ASP79
7ILE45-ASP92
4LEU5-ASP52

site_idPS00674
Number of Residues19
DetailsAAA AAA-protein family signature. TkIImATNrpdtLDpALl.R
ChainResidueDetails
LTHR321-ARG339
KVAL312-ARG330
MVAL321-ARG339
IVAL322-ARG340
JILE288-ARG306
HILE349-ARG367

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ZSER16
ZSER178
VASP122
CLYS231
dLYS100
dLYS199
dLYS231

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ZSER19
USER317
lLYS191

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358
ChainResidueDetails
ZTHR24
XSER140
ILYS255
ILYS290

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ZSER187
ZSER695

Catalytic Information from CSA
site_idMCSA1
Number of Residues8
DetailsM-CSA 177
ChainResidueDetails
2THR30covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
2ASP46activator, steric locator
2ARG48activator
2LYS62activator, electrostatic stabiliser
2GLY76electrostatic stabiliser
2SER158activator, electrostatic stabiliser
2ASP195activator, steric locator
2SER198activator, electrostatic stabiliser

site_idMCSA2
Number of Residues8
DetailsM-CSA 177
ChainResidueDetails
iTHR30covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
iASP46activator, steric locator
iARG48activator
iLYS62activator, electrostatic stabiliser
iGLY76electrostatic stabiliser
iSER158activator, electrostatic stabiliser
iASP195activator, steric locator
iSER198activator, electrostatic stabiliser

218196

PDB entries from 2024-04-10

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