6J2P

Crystal structure of Saccharomyces cerevisiae Spp1 in complex with H3K4me3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0048188	cellular_component	Set1C/COMPASS complex
B	0048188	cellular_component	Set1C/COMPASS complex
C	0048188	cellular_component	Set1C/COMPASS complex
D	0048188	cellular_component	Set1C/COMPASS complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	CYS39
A	CYS42
A	CYS66
A	CYS69

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 202

Chain	Residue
A	CYS93
A	CYS98
A	CYS109
A	HIS113

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 203

Chain	Residue
A	CYS27
A	HIS47
A	CYS50
A	CYS25

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN B 201

Chain	Residue
B	CYS25
B	CYS27
B	HIS47
B	CYS50

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN B 202

Chain	Residue
B	CYS39
B	CYS42
B	CYS66
B	CYS69

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN B 203

Chain	Residue
B	CYS93
B	CYS98
B	CYS109
B	HIS113

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	CYS25
C	CYS27
C	HIS47
C	CYS50

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN C 202

Chain	Residue
C	CYS39
C	CYS42
C	CYS66
C	CYS69
C	THR74

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN C 203

Chain	Residue
C	CYS93
C	CYS98
C	CYS109
C	HIS113

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN D 201

Chain	Residue
D	CYS25
D	CYS27
D	HIS47
D	CYS50

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN D 202

Chain	Residue
D	CYS39
D	CYS42
D	CYS66
D	CYS69

---

site_id	AD3
Number of Residues	3
Details	binding site for residue ZN D 203

Chain	Residue
D	CYS93
D	CYS98
D	CYS109

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	45
Details	ZF_PHD_1 Zinc finger PHD-type signature. Ci.Ckrpdygelm....................................VgCdg..Cddw.FHftClhipeqfkdlvfs................................FyCpyC

Chain	Residue	Details
A	CYS25-CYS69

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11742990, ECO:0000269|PubMed:11751634, ECO:0000269|PubMed:11752412, ECO:0000269|PubMed:12152067, ECO:0000269|PubMed:12353038, ECO:0000269|PubMed:12845608, ECO:0000269|PubMed:15949446, ECO:0000269|PubMed:16122352, ECO:0000269|PubMed:16168379, ECO:0000269|PubMed:16185711, ECO:0000269|PubMed:17194708

Chain	Residue	Details
E	M3L4
F	M3L4
G	M3L4
H	M3L4

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00146, ECO:0000269|PubMed:31253666, ECO:0007744|PDB:6J2P

Chain	Residue	Details
A	CYS25
B	CYS27
B	CYS39
B	CYS42
B	HIS47
B	CYS50
B	CYS66
B	CYS69
C	CYS25
C	CYS27
C	CYS39
A	CYS27
C	CYS42
C	HIS47
C	CYS50
C	CYS66
C	CYS69
D	CYS25
D	CYS27
D	CYS39
D	CYS42
D	HIS47
A	CYS39
D	CYS50
D	CYS66
D	CYS69
A	CYS42
A	HIS47
A	CYS50
A	CYS66
A	CYS69
B	CYS25

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:31253666, ECO:0007744|PDB:6J2P

Chain	Residue	Details
A	ASP97
C	CYS102
C	HIS113
C	PHE117
D	ASP97
D	CYS102
D	HIS113
D	PHE117
A	CYS102
A	HIS113
A	PHE117
B	ASP97
B	CYS102
B	HIS113
B	PHE117
C	ASP97

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	THR87
B	THR87
C	THR87
D	THR87

---