6J28
Crystal structure of the branched-chain polyamine synthase C9 mutein from Thermus thermophilus (Tth-BpsA C9) in complex with N4-aminopropylspermidine and 5'-methylthioadenosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006596 | biological_process | polyamine biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006596 | biological_process | polyamine biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue N4P A 401 |
| Chain | Residue |
| A | ASP133 |
| A | TYR295 |
| A | TRP298 |
| A | TYR300 |
| A | TYR321 |
| A | THR353 |
| A | MTA402 |
| A | HOH502 |
| A | HOH554 |
| A | GLN134 |
| A | GLY135 |
| A | ASP166 |
| A | ASP167 |
| A | ASP231 |
| A | PRO232 |
| A | GLU234 |
| A | GLU265 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue MTA A 402 |
| Chain | Residue |
| A | PHE132 |
| A | ASP133 |
| A | GLN134 |
| A | GLY164 |
| A | ASP165 |
| A | ASP166 |
| A | ASP186 |
| A | ALA187 |
| A | HIS211 |
| A | ASP212 |
| A | LEU213 |
| A | ASP231 |
| A | VAL233 |
| A | PHE242 |
| A | LEU345 |
| A | TYR346 |
| A | N4P401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 403 |
| Chain | Residue |
| A | CYS97 |
| A | CYS100 |
| C | CYS97 |
| C | CYS100 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue N4P B 401 |
| Chain | Residue |
| B | ASP133 |
| B | GLN134 |
| B | GLY135 |
| B | ASP166 |
| B | ASP167 |
| B | ASP231 |
| B | PRO232 |
| B | GLU234 |
| B | GLU265 |
| B | TYR295 |
| B | TRP298 |
| B | TYR300 |
| B | TYR321 |
| B | THR353 |
| B | MTA402 |
| B | HOH507 |
| B | HOH516 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue MTA B 402 |
| Chain | Residue |
| B | PHE132 |
| B | ASP133 |
| B | GLN134 |
| B | GLY164 |
| B | ASP165 |
| B | ASP166 |
| B | ASP186 |
| B | ALA187 |
| B | HIS211 |
| B | ASP212 |
| B | LEU213 |
| B | ASP231 |
| B | VAL233 |
| B | TYR346 |
| B | N4P401 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue FE B 403 |
| Chain | Residue |
| B | CYS97 |
| B | CYS100 |
| D | CYS97 |
| D | CYS100 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MES B 404 |
| Chain | Residue |
| A | ARG109 |
| B | GLU296 |
| B | ASN297 |
| C | GLU94 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue N4P C 401 |
| Chain | Residue |
| C | ASP133 |
| C | GLN134 |
| C | GLY135 |
| C | ASP166 |
| C | ASP167 |
| C | ASP231 |
| C | PRO232 |
| C | GLU234 |
| C | GLY260 |
| C | THR262 |
| C | TYR295 |
| C | TYR300 |
| C | TYR321 |
| C | THR353 |
| C | MTA402 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue MTA C 402 |
| Chain | Residue |
| C | ASP186 |
| C | ALA187 |
| C | HIS211 |
| C | ASP212 |
| C | LEU213 |
| C | ASP231 |
| C | VAL233 |
| C | PHE242 |
| C | TYR346 |
| C | N4P401 |
| C | PHE132 |
| C | ASP133 |
| C | GLN134 |
| C | GLY164 |
| C | ASP165 |
| C | ASP166 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MES C 403 |
| Chain | Residue |
| C | GLU219 |
| C | VAL222 |
| C | HIS223 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue N4P D 401 |
| Chain | Residue |
| D | ASP133 |
| D | GLN134 |
| D | GLY135 |
| D | ASP166 |
| D | ASP167 |
| D | ASP231 |
| D | PRO232 |
| D | GLU234 |
| D | GLY260 |
| D | THR262 |
| D | TRP298 |
| D | TYR300 |
| D | TYR321 |
| D | THR353 |
| D | MTA402 |
| D | HOH512 |
| site_id | AD3 |
| Number of Residues | 14 |
| Details | binding site for residue MTA D 402 |
| Chain | Residue |
| D | PHE132 |
| D | ASP133 |
| D | GLN134 |
| D | GLY164 |
| D | ASP165 |
| D | ASP166 |
| D | ASP186 |
| D | ALA187 |
| D | HIS211 |
| D | ASP212 |
| D | LEU213 |
| D | VAL233 |
| D | TYR346 |
| D | N4P401 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue MES D 403 |
| Chain | Residue |
| B | ASN151 |
| D | ARG53 |
| D | LEU54 |
| D | ARG56 |
| D | PRO92 |
| D | GLY93 |
| D | GLY291 |
| D | THR322 |
| D | HOH515 |
